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超声引导下骶管硬膜外注射治疗腰椎管狭窄症症状:一项回顾性研究。

Ultrasound-guided caudal epidural injection to treat symptoms of lumbar spinal stenosis: a retrospective study.

作者信息

Gagliardi Veronica, Lovato Antonello, Ceccherelli Francesco, Gagliardi Giuseppe

机构信息

AIRAS Padova, Italy; Department of Medicine, University of Padua.

AIRAS Padova.

出版信息

Eur J Transl Myol. 2024 May 7;34(2):12167. doi: 10.4081/ejtm.2024.12167.

Abstract

Lumbar spinal stenosis (LSS) occurs when bony, ligamentous, and synovial elements of the lower axial spine degenerate and overgrow, compressing neural and vascular elements in the spinal canal. Compression can cause static back pain, radicular lower extremity pain, or neurogenic claudication. Radiological and clinical findings are needed to diagnose lumbar stenosis. In this framework, caudal epidural steroid injection (ESI) is a standard treatment. The volume injected and needle positioning are the main issues that could compromise the effectiveness of the epidural injection. However, ultrasound-guided caudal epidural injections have become more common in recent years. Since Klocke and colleagues described the ultra-sound-guided caudal block in 2003, it has grown in popularity. Multiple ethnic studies have reported ultrasound-guided caudal injection success rates of 96.9-100%. Color Doppler ultrasonography can also determine if a drug solution reaches the lumbosacral region. We enrolled 42 patients with lumbar spinal stenosis, persistent lumbosciatalgia, and neurogenic claudicatio unresponsive to painkillers who were not surgical candidates. Each patient receives four weekly injections for four weeks. If the patient responds to treatment but still has pain, monthly injections are needed to reach and maintain the benefit. Treatment will be changed if the patient does not respond after 4 caudal injections. Sterile caudal epidural injections are performed with ultrasound guidance and a spinal needle 21G. Triamcinolone 40 mg, levobupivacaine 10 mg, and physiological solution 10 ml are delivered. Each patient received an average of 4 injective treatments (4±2, Means 4, SD 2). Data analysis shows that the treatment reduced pain significantly before and after therapy, which persisted after 3 months. Caudal epidural injection is one of the most common conservative treatments for chronic low back pain with radiculopathy, and lidocaine alone or with steroids is effective. In this framework, the two main literature issues about caudal epidural injection effectiveness on lumbar pain are correct. Therefore, 10 ml is suitable and effective for treating symptoms without side effects. Pain reduction of over 50% from start to finish and three-month follow-up have shown significant results in pain control and disability improvement. Finally, caudal epidural injection for lumbar spinal stenosis symptoms is effective, safe, and provides long-term pain relief.

摘要

当脊柱下段的骨质、韧带和滑膜组织发生退变并过度生长,压迫椎管内的神经和血管结构时,就会发生腰椎管狭窄症(LSS)。这种压迫可导致持续性背痛、下肢放射性疼痛或神经源性间歇性跛行。腰椎管狭窄症的诊断需要结合影像学和临床检查结果。在此背景下,骶管硬膜外类固醇注射(ESI)是一种标准治疗方法。注射量和进针位置是可能影响硬膜外注射效果的主要问题。然而,近年来超声引导下的骶管硬膜外注射越来越普遍。自2003年Klocke及其同事描述了超声引导下的骶管阻滞以来,其应用越来越广泛。多项不同种族研究报告超声引导下骶管注射的成功率为96.9%至100%。彩色多普勒超声还可确定药物溶液是否到达腰骶部区域。我们纳入了42例腰椎管狭窄症患者,这些患者持续存在腰腿痛和神经源性间歇性跛行,对止痛药无反应且不适合手术治疗。每位患者每周注射一次,共注射四周。如果患者对治疗有反应但仍有疼痛,则需要每月注射以维持疗效。如果患者在4次骶管注射后无反应,则改变治疗方案。在超声引导下使用21G脊椎穿刺针进行无菌骶管硬膜外注射。注射曲安奈德40mg、左旋布比卡因10mg和生理盐水10ml。每位患者平均接受4次注射治疗(4±2,均值4,标准差2)。数据分析表明,治疗前后疼痛均显著减轻,且在3个月后仍持续存在。骶管硬膜外注射是慢性下腰痛伴神经根病最常见的保守治疗方法之一,单独使用利多卡因或与类固醇联合使用均有效。在此背景下,关于骶管硬膜外注射对腰痛疗效的两个主要文献观点是正确的。因此,10ml的剂量适合且有效地治疗症状且无副作用。从开始到结束疼痛减轻超过50%,以及三个月的随访结果表明在疼痛控制和功能障碍改善方面取得了显著成效。最后,骶管硬膜外注射治疗腰椎管狭窄症的症状是有效、安全的,并能提供长期的疼痛缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dd44/11264217/81e0ae3265d6/ejtm-34-2-12167-g001.jpg

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