Bagley Carlos, MacAllister Matthew, Dosselman Luke, Moreno Jessica, Aoun Salah G, El Ahmadieh Tarek Y
Neurosurgery, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA.
F1000Res. 2019 Jan 31;8. doi: 10.12688/f1000research.16082.1. eCollection 2019.
Lumbar spinal stenosis is a degenerative process that is extremely frequent in today's aging population. It can result in impingement on the nerves of the cauda equina or on the thecal sac itself, and lead to debilitating symptoms such as severe leg pain, or restriction in the perimeter of ambulation, both resulting in dependency in daily activities. The impact of the disease is global and includes financial repercussions because of its involvement in the active work force group. Risk factors for the disease include some comorbidities such as obesity or smoking, daily habits such as an active lifestyle, but also genetic factors that are not completely elucidated yet. The diagnosis of lumbar stenosis can be difficult, and involves a combination of radiological and clinical findings. Treatment ranges from conservative measures with physical therapy and core strengthening, to steroid injections in the facet joints or epidural space, to a more radical solution with surgical decompression. The evidence available in the literature regarding the causes, diagnosis and treatment of lumbar spine stenosis can be confusing, as no level I recommendations can be provided yet based on current data. The aim of this manuscript is to provide a comprehensive and updated summary to the reader addressing the multiple aspects of this disease.
腰椎管狭窄症是一种退行性病变,在当今老龄化人群中极为常见。它可导致马尾神经或硬脊膜囊本身受到压迫,并引发诸如严重腿痛或行走范围受限等使人衰弱的症状,这两种情况都会导致日常生活依赖他人。该疾病的影响是全局性的,因其涉及劳动力群体,所以还包括经济影响。该疾病的风险因素包括一些合并症,如肥胖或吸烟,日常习惯,如积极的生活方式,以及尚未完全阐明的遗传因素。腰椎管狭窄症的诊断可能很困难,需要结合影像学和临床检查结果。治疗方法从物理治疗和核心肌群强化等保守措施,到小关节或硬膜外腔注射类固醇,再到手术减压等更激进的解决方案。由于目前的数据尚无法提供一级推荐,文献中关于腰椎管狭窄症病因、诊断和治疗的现有证据可能令人困惑。本文的目的是为读者提供一份全面且最新的总结,阐述该疾病的多个方面。
J Am Acad Orthop Surg. 2012-8
Praxis (Bern 1994). 2018-1
FP Essent. 2017-10
Semin Neurol. 2002-6
Z Rheumatol. 2015-4
Am Fam Physician. 1998-4-15
Nat Rev Neurol. 2009-7
Pain Pract. 2011-6-16
World Neurosurg. 2017-10-3
Neurosurgery. 2017-3-1
J Am Acad Orthop Surg. 2016-12
J Am Geriatr Soc. 2016-9-9
N Engl J Med. 2016-4-14
N Engl J Med. 2016-4-14
Spine (Phila Pa 1976). 2016-8-1