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Tubular CPT1A deletion minimally affects aging and chronic kidney injury.

作者信息

Hammoud Safaa, Ivanova Alla, Osaki Yosuke, Funk Steven, Yang Haichun, Viquez Olga, Delgado Rachel, Lu Dongliang, Phillips Mignemi Melanie, Tonello Jane, Colon Selene, Lantier Louise, Wasserman David H, Humphreys Benjamin D, Koenitzer Jeffrey, Kern Justin, de Caestecker Mark, Finkel Toren, Fogo Agnes, Messias Nidia, Lodhi Irfan J, Gewin Leslie S

出版信息

JCI Insight. 2024 May 8;9(9):e181816. doi: 10.1172/jci.insight.181816.

DOI:10.1172/jci.insight.181816
PMID:38716735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11141927/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf1/11141927/8caadca1972b/jciinsight-9-181816-g277.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf1/11141927/8caadca1972b/jciinsight-9-181816-g277.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bf1/11141927/8caadca1972b/jciinsight-9-181816-g277.jpg

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Tubular CPT1A deletion minimally affects aging and chronic kidney injury.肾小管CPT1A缺失对衰老和慢性肾损伤影响极小。
JCI Insight. 2024 May 8;9(9):e181816. doi: 10.1172/jci.insight.181816.
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Tubular CPT1A deletion minimally affects aging and chronic kidney injury.管状 CPT1A 缺失对衰老和慢性肾脏损伤的影响最小。
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Novel mutation in carnitine palmitoyltransferase 1A detected through newborn screening for a presymptomatic case in China: a case report.通过中国新生儿筛查发现肉毒碱棕榈酰转移酶 1A 的新突变：一例病例报告。
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[Analysis of a child with carnitine palmitoyl transferase 1A deficiency due to variant of CPT1A gene].[一例因肉碱棕榈酰转移酶1A（CPT1A）基因变异导致肉碱棕榈酰转移酶1A缺乏症患儿的分析]
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Biomolecules. 2025 May 29;15(6):794. doi: 10.3390/biom15060794.
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Tubule-Specific Compensatory Responses to Cpt1a Deletion in Aged Mice.衰老小鼠中肾小管特异性对肉碱棕榈酰转移酶1a缺失的代偿反应。
Kidney360. 2025 May 1;6(5):707-719. doi: 10.34067/KID.0000000746. Epub 2025 Mar 26.
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Assays to enhance metabolic phenotyping in the kidney.增强肾脏代谢表型分析的检测方法。
Am J Physiol Renal Physiol. 2025 Apr 1;328(4):F563-F577. doi: 10.1152/ajprenal.00232.2024. Epub 2025 Jan 17.
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Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation.肺泡上皮细胞通过调节线粒体脂肪酸氧化减轻肺损伤中的中性粒细胞炎症。
Nat Commun. 2024 Aug 22;15(1):7241. doi: 10.1038/s41467-024-51683-1.