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揭示约旦儿科中毒中曼陀罗的阴暗面:一项回顾性临床研究。

Unveiling the Dark Side of Datura in Pediatric Poisoning With Insights From Jordanian Experience : A Retrospective Clinical Study.

机构信息

From the Pediatric Department, Faculty of Medicine, Mutah University, Karak 61710, Jordan.

Pediatric Department Faculty of Medicine, Mutah University, Karak 61710, Jordan.

出版信息

Pediatr Emerg Care. 2024 Jul 1;40(7):541-546. doi: 10.1097/PEC.0000000000003189. Epub 2024 May 9.

Abstract

OBJECTIVES

Datura stramonium , jimsonweed, is a toxic plant with hallucinogenic properties. Although there are many studies on Datura poisoning, none reported cases in Jordan. This study offers a comprehensive review on D. stramonium ingestion, covering its epidemiology, clinical presentation, and treatment. We aimed to provide better understanding of the factors for Datura ingestion, identify prevention and management strategies, and address research challenges.

METHODS

This study adopted a retrospective review design to evaluate the cases of Datura poisoning in Al Karak, province of Jordan during the spring of 2022. Data collected from medical records, toxicology databases, and consultation records were analyzed using descriptive statistics.

RESULTS

The common symptoms of Datura poisoning included agitation, mydriasis, and tachycardia. The management approaches comprised supportive care, administration of Diazepam for agitation, and, in some cases, neostigmine to counteract anticholinergic effects.

CONCLUSIONS

Understanding the risks associated with D. stramonium poisoning and implementing effective prevention and management strategies are crucial. This study highlights the importance of recognizing Datura poisoning as a potential diagnosis in children presenting with unexplained anticholinergic symptoms or agitation to the emergency room.

摘要

目的

曼陀罗,颠茄,是一种具有致幻特性的有毒植物。尽管有许多关于颠茄中毒的研究,但在约旦没有报告过此类病例。本研究对颠茄中毒进行了全面回顾,涵盖其流行病学、临床表现和治疗。我们旨在更好地了解颠茄摄入的因素,确定预防和管理策略,并解决研究挑战。

方法

本研究采用回顾性研究设计,评估 2022 年春季约旦卡尔卡省颠茄中毒的病例。从病历、毒理学数据库和咨询记录中收集的数据采用描述性统计进行分析。

结果

颠茄中毒的常见症状包括激动、瞳孔散大和心动过速。管理方法包括支持性治疗、给予地西泮治疗激动、以及在某些情况下给予新斯的明以对抗抗胆碱能作用。

结论

了解与曼陀罗中毒相关的风险,并实施有效的预防和管理策略至关重要。本研究强调了在急诊室出现不明原因抗胆碱能症状或激动的儿童中识别颠茄中毒作为潜在诊断的重要性。

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