Department of Periodontology, Korea University Anam Hospital, Seoul, Republic of Korea.
Department of Biostatistics, Korea University College of Medicine, Seoul, Republic of Korea.
BMC Oral Health. 2024 May 8;24(1):539. doi: 10.1186/s12903-024-04270-1.
This study aimed to demonstrate the efficacy of erbium, chromium-doped:yttrium, scandium, gallium, and garnet (Er,Cr:YSGG) laser-assisted nonsurgical periodontal therapy in periodontitis patients during 8 weeks of healing.
A split-mouth, single-blinded, randomized controlled clinical trial was conducted on 12 patients diagnosed with stage III/IV periodontitis and had a minimum of two teeth with probing pocket depth (PPD) > 5 mm in at least two quadrants. Upon randomization, each quadrant was assigned for conventional scaling and root planing (SRP) procedure or laser-assisted therapy (SRP + laser) using radial firing tip (RFPT 5, Biolase). Clinical measurements and gingival crevicular fluid collection were performed for statistical analysis.
In the initial statistical analysis on the whole subject teeth, modified gingival index (MGI) reduction was greater in test group at 1(P = 0.0153), 4 (P = 0.0318), and 8 weeks (P = 0.0047) compared to the control in the same period. PPD reduction at 4 weeks in test group was -1.67 ± 0.59 showing significant difference compared to the control (-1.37 ± 0.63, P = 0.0253). When teeth with mean PPD ≥5 mm were sorted, MGI decrease was significantly greater in test group at 1 (P=0.003) and 8 week (P=0.0102) follow-ups. PPD reduction was also significantly greater in test group at 4 week period (-1.98 ± 0.55 vs -1.58 ± 0.56, test vs control, P=0.0224).
Er,Cr:YSGG-assisted periodontal therapy is beneficial in MGI and PPD reductions during early healing period.
本研究旨在展示铒铬：钇、钪、镓、石榴石（Er，Cr：YSGG）激光辅助非手术牙周治疗在牙周炎患者 8 周愈合期间的疗效。
采用分口、单盲、随机对照临床试验，对 12 名诊断为 III/IV 期牙周炎且至少有两颗牙的探诊袋深（PPD）>5mm 的患者进行研究，至少有两个象限。随机分组后，每个象限分别进行常规牙周刮治和根面平整术（SRP）或激光辅助治疗（SRP+激光），使用放射状发射尖端（RFPT 5，Biolase）。进行临床测量和龈沟液采集，进行统计分析。
在整个受试牙的初始统计分析中，在第 1 周（P=0.0153）、第 4 周（P=0.0318）和第 8 周（P=0.0047）时，试验组的改良牙龈指数（MGI）降低大于对照组。在第 4 周时，试验组的 PPD 降低为-1.67±0.59，与对照组相比有显著差异（-1.37±0.63，P=0.0253）。当按照平均 PPD≥5mm 的牙齿进行分类时，在第 1 周（P=0.003）和第 8 周（P=0.0102）随访时，试验组的 MGI 下降更为显著。在第 4 周时，试验组的 PPD 降低也更为显著（-1.98±0.55 与-1.58±0.56，试验组与对照组，P=0.0224）。
Er，Cr：YSGG 辅助牙周治疗在早期愈合期有利于 MGI 和 PPD 的降低。
