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子宫内膜癌小肠转移最初表现为肠皮肤瘘:一例报告及文献复习

Small intestine metastasis from endometrial carcinoma initially presented as enterocutaneous fistula: a case report and literature review.

作者信息

Nikolovski Andrej, Limani Nimetula, Ristova Tancheva Aleksandra, Manasievska Bogoevska Antonela, Krsteska Blagica

机构信息

Department of Visceral Surgery. University Surgery Hospital "St. Naum Ohridski", Skopje 1000, North Macedonia.

Medical Faculty in Skopje, Ss. Cyril and Methodius University in Skopje, Skopje 1000, North Macedonia.

出版信息

J Surg Case Rep. 2024 May 7;2024(5):rjae297. doi: 10.1093/jscr/rjae297. eCollection 2024 May.

Abstract

Although endometrial cancer is the fourth most common malignancy among women, it rarely metastasizes to the small intestine. Cases of endometrial recurrence to the intestine clinically present with secondary anemia, melena, abdominal cramps, and epigastric pain. Only a dozen cases are reported in the literature, but none presented with an enterocutaneous fistula. In this report, we present a case of an 88-year-old female patient previously treated for endometrial adenocarcinoma with surgery and adjuvant radiotherapy. Fourteen months after the surgery, the patient presented with an enterocutaneous fistula on the anterior abdominal wall, which was confirmed to be a metastasis from the primary tumor. To our knowledge, this is the first case of endometrial cancer metastasizing to the small intestine with involvement of the anterior abdominal wall and the occurrence of an enterocutaneous fistula, which was treated with radical surgery.

摘要

尽管子宫内膜癌是女性中第四常见的恶性肿瘤,但它很少转移至小肠。子宫内膜癌复发至肠道的病例临床上表现为继发性贫血、黑便、腹部绞痛和上腹部疼痛。文献中仅报道了十几例,但均未出现肠皮肤瘘。在本报告中,我们呈现了一例88岁女性患者,她曾接受子宫内膜腺癌手术及辅助放疗。术后14个月,患者前腹壁出现肠皮肤瘘,经证实为原发性肿瘤转移所致。据我们所知,这是首例子宫内膜癌转移至小肠并累及前腹壁且出现肠皮肤瘘的病例,该病例接受了根治性手术治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3eb/11078053/d1a019a38a8d/rjae297f1.jpg

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