Tali Nguefak Lionel Danny, Faujo Nintewoue Ghislaine Florice, Stanley Ngimgoh Ngemeshe, Talla Paul, Ngatcha Ghislaine, Tagni Sartre Michele, Jude-Marcel Nzoume Nsope Mengang, Paul Dzoyem Jean, Kouitcheu Mabeku Laure Brigitte
Microbiology and Pharmacology Laboratory, Department of Biochemistry, Faculty of Science University of Dschang Dschang Cameroon.
Department of Gastroenterology General Hospital Yaoundé Yaoundé Cameroon.
JGH Open. 2024 May 8;8(5):e13060. doi: 10.1002/jgh3.13060. eCollection 2024 May.
represents the major pathogen in the pathophysiology of diverse gastrointestinal conditions. This study sought to determine the endoscopic aspect of the gastric mucosa in relation to infection in Cameroon.
This study was conducted in three reference health facilities in Cameroon from October 2020 to October 2022. The study enrolled 494 consecutive volunteer dyspeptic patients attending to the gastroenterology department of the selected health facilities. A description of the aspect of gastric mucosa of all participants was performed during endoscopy examination, and biopsies were collected for detection using rapid urease tests.
Gastritis, ulcerated lesions, duodenitis, esophagitis, normal mucosa aspect, bulbitis, and gastric neoplastic lesions were found in 40.1, 22.3, 10.9, 10.3, 9.7, 6.3, and 0.40% of biopsy samples, respectively. Erythematous/exudative (45.9%) and enterogastric reflux (12.2%) were the main gastritis types recorded. was present in 58.1, 46.3, 87.1, 66.7, and 61.8% in gastritis, duodenitis, bulbitis, esophagitis, and ulcerated lesions, respectively. A positive relationship was noticed between the presence of and gastritis (1.037 [0.720-1.493]; = 0.845), bulbitis (4.237 [1.602-11.235]; = 0.004), esophagitis (1.515 [0.822-2.793]; = 0.183), ulcerated lesions (1.233 [0.798-1.904]; = 0.345), erythematous/exudative gastritis (1.354 [0.768-2.389]; = 0.295), and enterogastric reflux gastritis (1.159 [0.492-2.733]; = 0.736).
Gastritis and erythematous/exudative gastritis are the most frequent gastrointestinal pathophysiology conditions in dyspeptic patient in our milieu. infection is responsible for 94.8% of the gastrointestinal pathophysiology conditions with bulbitis as the condition is significantly associated with this bacterium infection.
[某种细菌]是多种胃肠道疾病病理生理学中的主要病原体。本研究旨在确定喀麦隆与[该细菌]感染相关的胃黏膜内镜表现。
本研究于2020年10月至2022年10月在喀麦隆的三个参考卫生机构进行。该研究纳入了494名连续就诊于选定卫生机构胃肠病科的消化不良志愿者患者。在内镜检查期间对所有参与者的胃黏膜表现进行描述，并采集活检样本用快速尿素酶试验进行[该细菌]检测。
在活检样本中，胃炎、溃疡性病变、十二指肠炎、食管炎、正常黏膜表现、球炎和胃肿瘤性病变分别占40.1%、22.3%、10.9%、10.3%、9.7%、6.3%和0.40%。记录到的主要胃炎类型为红斑/渗出性（45.9%）和肠胃反流（12.2%）。[该细菌]在胃炎、十二指肠炎、球炎、食管炎和溃疡性病变中的检出率分别为58.1%、46.3%、87.1%、66.7%和61.8%。观察到[该细菌]的存在与胃炎（1.037 [0.720 - 1.493]；P = 0.845）、球炎（4.237 [1.602 - 11.235]；P = 0.004）、食管炎（1.515 [0.822 - 2.793]；P = 0.183）、溃疡性病变（1.233 [0.798 - 1.904]；P = 0.345）、红斑/渗出性胃炎（1.354 [0.768 - 2.389]；P = 0.295）和肠胃反流性胃炎（1.159 [0.492 - 2.733]；P = 0.736）之间存在正相关关系。
在我们所处环境中，胃炎和红斑/渗出性胃炎是消化不良患者中最常见的胃肠道病理生理状况。[该细菌]感染导致了94.8%的胃肠道病理生理状况，球炎与这种细菌感染显著相关。
