Basic Medical Sciences Department, College of Medicine, Ajman University, Ajman, UAE.
Faculty of Dentistry, 105956 MAHSA University , Jenjarom, Selangor, Malaysia.
Horm Mol Biol Clin Investig. 2024 May 10;45(2):41-47. doi: 10.1515/hmbci-2023-0063. eCollection 2024 Jun 1.
Digit ratio (2D:4D), as endocrine fingerprint, can indicate prenatal androgen exposure. It serves as an anatomical marker for various systemic diseases and a few studies relating it to oral health. The present study aims to evaluate the association between digit ratio and susceptibility to dental plaque formation.
The study was conducted on young adults aged between 18 and 25 years. Digit ratio and reproductive hormones were measured; dental plaque score and gingival index (GI) were recorded. Data were analysed using the MedCalc. v.20.
Male and female participants were categorized into two groups based on their digit ratios being either above or below the calculated average (0.99 for females, 0.98 for males). Those with a digit ratio below the average had a significantly higher mean dental plaque score (p < 0.0001) than those with ratios at or above the average. However, there was no significant difference in the GI between the two groups. Reproductive hormone profiles varied significantly between the higher and lower digit ratio groups for both sexes.
Digit ratio may find potential to be used as an anatomical marker to identify the susceptibility to dental plaque build-up.
二四指比（2D:4D）作为内分泌指纹，可以指示产前雄激素暴露。它是各种系统性疾病的解剖学标志物，并且有一些研究将其与口腔健康相关联。本研究旨在评估二四指比与牙菌斑形成易感性之间的关系。
该研究对象为 18 至 25 岁的年轻人。测量了二四指比和生殖激素；记录了牙菌斑评分和牙龈指数（GI）。使用 MedCalc. v.20 分析数据。
根据二四指比高于或低于计算平均值（女性为 0.99，男性为 0.98），将男性和女性参与者分为两组。二四指比低于平均值的组的平均牙菌斑评分显著更高（p < 0.0001），而比率等于或高于平均值的组则没有显著差异。然而，两组之间的 GI 没有显著差异。对于两性，较高和较低二四指比组之间的生殖激素谱差异显著。
二四指比可能有潜力用作解剖学标志物，以识别牙菌斑堆积的易感性。
