Division of Cardiology, Shimane University Faculty of Medicine, Shimane, Japan.
Division of Cardiology, Masuda Red Cross Hospital, Shimane, Japan.
Medicine (Baltimore). 2024 May 10;103(19):e38159. doi: 10.1097/MD.0000000000038159.
Shear wave elastography (SWE) is a noninvasive method for measuring organ stiffness. Liver stiffness measured using SWE reflects hepatic congestion in patients with heart failure (HF). However, little is known about the use of SWE to assess other organ congestions. This study aimed to evaluate the utility of SWE for assessing not only the liver but also thyroid congestion in patients with HF. This prospective study included 21 patients with HF who have normal thyroid lobes (age: 77.0 ± 11.0, men: 14). Thyroid and liver stiffness were measured by SWE using the ARIETTA 850 ultrasonography system (Fujifilm Ltd., Tokyo, Japan). SWE of the thyroid was performed on B-mode ultrasonography; a target region was identified within a region of interest. SWE was performed in each lobe of the thyroid gland. Five measurements were taken at the same location and the averages were recorded for comparison. We investigated the relationship between SWE for evaluating thyroid stiffness and the clinical characteristics of patients with HF. SWE of the thyroid was significantly correlated with SWE of the liver (R = 0.768, P < .001), thyroid stimulation hormone (R = 0.570, P = .011), free thyroxine (R = 0.493, P = .032), estimated right atrial pressure (RAP; R = 0.468, P = .033), and composite congestion score (R = 0.441, P = .045). SWE may be useful for evaluating thyroid stiffness and assessing the degree of thyroid congestion. Thyroid congestion may reflect the elevation of RAP and cause thyroid dysfunction through organ congestion.
剪切波弹性成像（SWE）是一种测量器官硬度的无创方法。使用 SWE 测量的肝脏硬度反映了心力衰竭（HF）患者的肝充血。然而，对于使用 SWE 评估其他器官充血的方法知之甚少。本研究旨在评估 SWE 不仅可用于评估肝脏，还可用于评估 HF 患者的甲状腺充血。这项前瞻性研究纳入了 21 名甲状腺正常的 HF 患者（年龄：77.0±11.0，男性：14 人）。使用 ARIETTA 850 超声系统（富士胶片有限公司，日本东京）通过 SWE 测量甲状腺和肝脏硬度。在 B 模式超声上进行甲状腺 SWE；在感兴趣区域内确定目标区域。在甲状腺的每个叶中进行 SWE。在同一位置进行 5 次测量，并记录平均值以进行比较。我们研究了评估甲状腺硬度的 SWE 与 HF 患者临床特征之间的关系。甲状腺 SWE 与肝脏 SWE 显著相关（R=0.768，P<.001）、促甲状腺激素（R=0.570，P=.011）、游离甲状腺素（R=0.493，P=.032）、估计右心房压（RAP；R=0.468，P=.033）和综合充血评分（R=0.441，P=.045）。SWE 可能有助于评估甲状腺硬度和评估甲状腺充血程度。甲状腺充血可能反映 RAP 的升高，并通过器官充血导致甲状腺功能障碍。
