Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California.
University of California, San Diego, La Jolla, California.
J AAPOS. 2024 Jun;28(3):103936. doi: 10.1016/j.jaapos.2024.103936. Epub 2024 May 9.
Presently, little is known regarding the characteristics and publication rates of registered strabismus trials from ClinicalTrials.gov. We queried registered strabismus trials that were completed prior to January 1, 2021, from ClinicalTrials.gov. Publication of trials in peer-reviewed journals was confirmed using PubMed.gov, ClinicalTrials.gov, and Google Scholar. Of the 117 trials found, only 69 (59%) were published with a publication delay of nearly 2.5 years. Interventional trials were associated with publication status compared with observational trials. The low publication rates and significant publication delay indicate potential bias in information dissemination of completed strabismus trials.
目前，对于 ClinicalTrials.gov 上注册斜视试验的特征和发表率知之甚少。我们从 ClinicalTrials.gov 中查询了 2021 年 1 月 1 日之前完成的注册斜视试验。使用 PubMed.gov、ClinicalTrials.gov 和 Google Scholar 确认了试验在同行评议期刊上的发表情况。在 117 项试验中，只有 69 项（59%）发表了，发表延迟近 2.5 年。与观察性试验相比，干预性试验与发表状态相关。低发表率和显著的发表延迟表明斜视试验完成后信息传播存在潜在偏差。
