Department of Neurology, UT Southwestern Medical Center, Dallas, Texas, USA.
Department of Pathology, UT Southwestern Medical Center, Dallas, Texas, USA.
BMJ Case Rep. 2024 May 10;17(5):e259803. doi: 10.1136/bcr-2024-259803.
Ependymomas are neuroepithelial tumours arising from ependymal cells surrounding the cerebral ventricles that rarely metastasise to extraneural structures. This spread has been reported to occur to the lungs, lymph nodes, liver and bone. We describe the case of a patient with recurrent CNS WHO grade 3 ependymoma with extraneural metastatic disease. He was treated with multiple surgical resections, radiation therapy and salvage chemotherapy for his extraneural metastasis to the lungs, bone, pleural space and lymph nodes.
室管膜瘤是起源于脑室周围的神经上皮肿瘤,很少向神经外结构转移。这种转移已被报道发生在肺部、淋巴结、肝脏和骨骼。我们描述了一例复发性 CNS 世界卫生组织 3 级室管膜瘤伴神经外转移疾病的患者。他曾接受多次手术切除、放疗和挽救性化疗,以治疗肺部、骨骼、胸膜腔和淋巴结的神经外转移。