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[外周性阵发性良性位置性眩晕的病理生理学]

[Pathophysiology of peripheral, paroxysmal benign position vertigo].

作者信息

Schmidt C L

出版信息

Laryngol Rhinol Otol (Stuttg). 1985 Mar;64(3):146-55.

PMID:3872984
Abstract

Peripheral paroxysmal, benign positional vertigo is one of the most common peripheral vestibular disorders. According to the "cupulolithiasis hypothesis", it is assumed that inorganic material is attached to the cupula of the posterior vertical canal which renders this organ sensitive to gravitational forces rather than angular accelerations. Quantitative and well-controlled positioning manoeuvres, however, show that the characteristics of this kind of vertigo and the corresponding nystagmus cannot be explained by gravitation-dependent cupular reactions. It seems more probable that the typical symptoms are caused by disturbed utricular functions leading to disinhibited responses of the posterior vertical canal to adequate stimuli.

摘要

外周性阵发性良性位置性眩晕是最常见的外周性前庭疾病之一。根据“嵴顶结石症假说”,推测无机物质附着于后半规管的壶腹嵴,这使得该器官对重力而非角加速度敏感。然而,定量且严格控制的定位操作表明,这种眩晕及相应眼震的特征无法用依赖重力的壶腹反应来解释。典型症状更有可能是由椭圆囊功能紊乱导致后半规管对适当刺激的反应不受抑制所引起的。

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