Revenco Diomid, Hakenová Martina Fialová, Mestek Oto, Koplík Richard
Department of Food Analysis and Nutrition, University of Chemistry and Technology, Prague 6, 166 28 Prague, Czech Republic.
Department of Analytical Chemistry, University of Chemistry and Technology, Prague 6, 166 28 Prague, Czech Republic.
Foods. 2024 Apr 24;13(9):1311. doi: 10.3390/foods13091311.
Silver nanoparticles (AgNPs), widely used in various fields of technology as an antimicrobial agent, represent a new type of environmental pollutant. Through various routes, AgNPs might penetrate into agricultural crops and foodstuffs. It is important to know if AgNPs contained in food persist in digested food and are therefore available for entering the inner organs of the consumer's body. Using the technique of single-particle ICP-MS, we analysed the changes in the number and size distribution of AgNPs added to a sample of bread submitted to in vitro simulated gastrointestinal digestion. The majority of silver, in terms of mass, was transformed from the state of particles to the dissolved state during bread digestion, but the number of particles was reduced by 25% only. The most abundant particle size was reduced from 60 nm to 49 nm. Hence, a substantial part of transformed nanoparticles is still present in food digestate. This means that AgNPs consumed together with food can theoretically enter the inner cells of human body.
银纳米颗粒（AgNPs）作为一种抗菌剂被广泛应用于各个技术领域，它是一种新型的环境污染物。通过各种途径，AgNPs可能会渗透到农作物和食品中。了解食品中所含的AgNPs在消化后的食物中是否仍然存在，从而是否有可能进入消费者体内的内部器官，这一点很重要。我们使用单颗粒电感耦合等离子体质谱技术，分析了添加到面包样品中的AgNPs在体外模拟胃肠道消化过程中数量和尺寸分布的变化。在面包消化过程中，从质量方面来看，大部分银从颗粒状态转变为溶解状态，但颗粒数量仅减少了25%。最丰富的颗粒尺寸从60纳米减小到49纳米。因此，相当一部分转化后的纳米颗粒仍存在于食物消化物中。这意味着与食物一起摄入的AgNPs理论上可以进入人体的内部细胞。
