Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul, Campo Grande 79079-900, Brazil.
State University of Mato Grosso do Sul (UEMS), Dourados 79804-970, Brazil.
Nutrients. 2024 Apr 30;16(9):1363. doi: 10.3390/nu16091363.
Oncological patients show intense catabolic activity, as well as a susceptibility to higher nutritional risk and clinical complications. Thus, tools are used for monitoring prognosis. Our objective was to analyze the nutrition prognosis of patients who underwent radiotherapy, correlating it with outcomes and complications. We performed a retrospective transversal study based on secondary data from hospital records of patients who started radiotherapy between July 2022 and July 2023. We established Prognostic Scores through a combination of Prognostic Nutritional Index (PNI) and a Subjective Global Assessment (SGA), assessed at the beginning and end of treatment. Score 3 patients, with PNI ≤ 45.56 and an SGA outcome of malnutrition, initially presented a higher occurrence of odynophagia, later also being indicative of reduced diet volume, treatment interruption, and dysphagia. SGA alone showed sensitivity to altered diet volume, dysphagia, and xerostomia in the second assessment. Besides this, PNI ≤ 45.56 also indicated the use of alternative feeding routes, treatment interruption, and hospital discharge with more complications. We conclude that the scores could be used to indicate complications; however, further studies on combined biomarkers are necessary.
肿瘤患者表现出强烈的分解代谢活性，以及更高的营养风险和临床并发症易感性。因此，使用了一些工具来监测预后。我们的目的是分析接受放疗的患者的营养预后，并将其与结局和并发症相关联。我们进行了一项回顾性的横断面研究，基于 2022 年 7 月至 2023 年 7 月间开始放疗的患者的医院记录中的二级数据。我们通过结合预后营养指数（PNI）和主观整体评估（SGA）建立了预后评分，在治疗开始和结束时进行评估。评分 3 的患者，PNI≤45.56，SGA 结果为营养不良，最初表现为吞咽困难的发生率更高，后来也表明饮食量减少、治疗中断和吞咽困难。单独的 SGA 在第二次评估中对饮食量改变、吞咽困难和口干敏感。此外，PNI≤45.56 还表明需要使用替代喂养途径、治疗中断以及出现更多并发症的出院。我们得出结论，这些评分可用于指示并发症；然而，有必要进行关于联合生物标志物的进一步研究。
