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4 岁女童维生素 A 缺乏致双侧巴氏腺脓肿:病例报告。

Bilateral bartholin's gland abscesses in a 4-year-old girl with vitamin a deficiency: a case report.

机构信息

Department of Obstetrics, Hyogo Prefectural Kobe Children's Hospital, 1-6-7, Minatojimaminamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.

Department of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tamba, Japan.

出版信息

BMC Infect Dis. 2024 May 11;24(1):487. doi: 10.1186/s12879-024-09382-1.

Abstract

BACKGROUND

A Bartholin's gland abscess is one of the most common infections in women of reproductive age. Although Bartholin's gland abscesses have been reported in prepubertal children, they are rarer in prepubertal children than in adults. Herein, we report a case of bilateral Bartholin's gland abscesses in a 4-year-old girl with vitamin A deficiency.

CASE PRESENTATION

A 4-year-old girl diagnosed with autism spectrum disorder was admitted to the hospital for close examination and treatment because of persistent fever and malaise. The child was a marked fussy eater and was diagnosed with corneal ulceration and night blindness secondary to vitamin A deficiency. Both of the patient's labia were swollen, and a diagnosis of a bilateral Bartholin's gland abscess was made using computed tomography. Incisional drainage was performed under general anesthesia. The patient's postoperative course was uneventful, and she was discharged from the hospital on day 8 after the surgery. During hospitalization, attempts were made to correct the vitamin deficiency by adding nutritional supplements to the diet. Three months after the surgery, no recurrence of abscesses was noted.

CONCLUSIONS

Decreased immunocompetence and mucosal barrier function due to vitamin A deficiency is thought to be the underlying cause of Bartholin's gland abscesses. Although prepubertal Bartholin's gland abscesses have been reported, they are rare. To the best of our knowledge, no reports of bilateral Bartholin's gland abscesses potentially caused by vitamin A deficiency have been reported. When prepubertal girls present with Bartholin's gland abscesses, the presence of immunodeficiency due to vitamin or trace element deficiency should also be considered.

摘要

背景

巴氏腺脓肿是育龄期妇女最常见的感染之一。虽然巴氏腺脓肿在青春期前儿童中已有报道,但在青春期前儿童中比在成年人中少见。在此,我们报告一例 4 岁女孩因维生素 A 缺乏引起的双侧巴氏腺脓肿。

病例介绍

一名被诊断为自闭症谱系障碍的 4 岁女孩因持续发热和不适入院接受密切检查和治疗。该患儿为明显的挑食者,被诊断为维生素 A 缺乏引起的角膜溃疡和夜盲症。患儿的阴唇均肿胀,经计算机断层扫描诊断为双侧巴氏腺脓肿。在全身麻醉下进行切开引流。患者术后恢复顺利,术后第 8 天出院。住院期间,通过添加营养补充剂来纠正维生素缺乏。术后 3 个月,未发现脓肿复发。

结论

维生素 A 缺乏导致的免疫功能下降和黏膜屏障功能下降被认为是巴氏腺脓肿的潜在病因。虽然青春期前巴氏腺脓肿已有报道,但很少见。据我们所知,尚无报道称双侧巴氏腺脓肿可能由维生素 A 缺乏引起。当青春期前女孩出现巴氏腺脓肿时,也应考虑因维生素或微量元素缺乏引起的免疫缺陷。

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