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系统评价和荟萃分析外科医生-医师共管模式对血管外科住院患者短期结局的影响。

Systematic Review and Meta-analysis of the Impact of Surgeon-Physician Co-management Models on Short Term Outcomes for Vascular Surgery Inpatients.

机构信息

University College Hospital Galway, Galway, Ireland; Royal College of Surgeons in Ireland, Dublin, Ireland.

University College Hospital Galway, Galway, Ireland.

出版信息

Eur J Vasc Endovasc Surg. 2024 Sep;68(3):336-345. doi: 10.1016/j.ejvs.2024.05.005. Epub 2024 May 11.

Abstract

OBJECTIVE

As the population ages, vascular surgeons are treating progressively older, multimorbid patients at risk of peri-operative complications. An embedded physician has been shown to improve outcomes in general and orthopaedic surgery. This systematic review and meta-analysis aimed to investigate the impact of surgeon-physician co-management models on morbidity and mortality rates in vascular inpatients.

DATA SOURCES

PubMed, Scopus, Embase, conference abstract listings, and clinical trial registries.

REVIEW METHODS

Studies comparing adult vascular surgery inpatients under co-management with standard of care were eligible. The relative risks (RRs) of death, medical complications, and 30 day re-admission between co-management and standard care were calculated. The effect of co-management on the mean length of stay was calculated using weighted means. Risk of bias was assessed using the Methodological Index for Non-Randomised Studies, and certainty assessment with the GRADE analysis tools.

RESULTS

No randomised controlled trials were identified. Eight single institution studies between 2011 and 2020 with 7 410 patients were included. All studies were observational using before-after methodology. Studies were of high to moderate risk of bias, and outcomes were of very low GRADE certainty of evidence. Co-management was associated with a statistically significant lower relative risk of death (RR 0.64, 95% confidence interval [CI] 0.44 - 0.92; p = .02), cardiac complications (RR 0.47, 95% CI 0.25 - 0.87; p = .02), and infective complications (RR 0.49, 95% CI 0.35 - 0.67; p < .001) in vascular inpatients. No statistically significant differences in length of stay (standard mean difference -0.6 days, 95% CI -1.44 - 0.24 days; p = .16) and 30 day re-admission (RR 0.96, 95% CI 0.84 - 1.08; p = .49) were noted.

CONCLUSION

Early results of physician and surgeon co-management for vascular surgery inpatients showed promising results from very low certainty data. Further well designed, prospective studies are needed to determine how to maximise the impact of physicians within a vascular service to improve patient outcomes while using hospital resources effectively.

摘要

目的

随着人口老龄化,血管外科医生治疗的患者年龄越来越大,合并症也越来越多,存在围手术期并发症的风险。已经证明,在普通外科和骨科手术中嵌入医生可以改善预后。本系统评价和荟萃分析旨在研究血管住院患者的外科医生-医生共同管理模式对发病率和死亡率的影响。

数据来源

PubMed、Scopus、Embase、会议摘要列表和临床试验注册处。

研究方法

符合条件的研究比较了共同管理下的成人血管外科住院患者与标准护理的比较。共同管理与标准护理之间的死亡率、医疗并发症和 30 天再入院的相对风险 (RR) 以及共同管理对平均住院时间的影响使用加权均值进行计算。使用非随机研究方法学指数 (Methodological Index for Non-Randomised Studies, MINORS) 评估偏倚风险,并使用 GRADE 分析工具评估确定性。

结果

未确定随机对照试验。纳入了 2011 年至 2020 年间的 8 项单机构研究,共 7410 例患者。所有研究均采用前后对照方法,采用观察性研究。研究的偏倚风险较高至中度,结局的证据确定性非常低。共同管理与死亡率的相对风险显著降低相关(RR 0.64,95%置信区间 [CI] 0.44-0.92;p=0.02)、心脏并发症(RR 0.47,95% CI 0.25-0.87;p=0.02)和感染性并发症(RR 0.49,95% CI 0.35-0.67;p<0.001)。在血管住院患者中,住院时间(标准均数差-0.6 天,95% CI-1.44-0.24 天;p=0.16)和 30 天再入院(RR 0.96,95% CI 0.84-1.08;p=0.49)的差异无统计学意义。

结论

血管外科住院患者的医生和外科医生共同管理的早期结果显示,来自非常低确定性数据的结果有希望。需要进一步进行精心设计的前瞻性研究,以确定如何在血管服务中最大限度地发挥医生的作用,改善患者预后,同时有效利用医院资源。

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