Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Ital J Pediatr. 2024 May 12;50(1):96. doi: 10.1186/s13052-024-01642-9.
In 1974, the World Health Organization (WHO) established the Expanded Program on Immunization to control vaccine-preventable diseases, saving millions of lives annually. However, the coverage of basic vaccines recommended by the WHO in Africa was only 75%, which fell short of the goal of 90% by 2015. To formulate effective policies and implementation programs to reduce incomplete vaccination rates, it is important to conduct a study to determine the factors contributing to incomplete immunization among children aged 12-23 months.
The study was conducted in 16 sub-Saharan African countries, using data extracted from the latest DHS data. It was a community-based cross-sectional survey that used two-stage stratified probability sampling sample designs. The vaccination coverage was assessed using vaccination cards and mother recalls. Multilevel multivariable logistic regression was used to determine the extent of incomplete immunization and the individual and community-level factors associated with partial immunization among children aged 12-23 months. Variables with a p-value less than 0.05 were considered statistically significant predictors of incomplete immunization.
A total of 35, 193 weighted samples were used to determine the pooled prevalence of partial immunization. The pooled prevalence of incomplete immunization was 36.06%. In the final model factors significantly associated were: being uneducated mother(AOR:1.75;95%CI:1.48,2.05), being an unemployed mother (AOR:1.16;95%CI:1.09,1.23), no history of family planning utilization (AOR: 1.71; 95% CI: 1.61, 1.84), non-antenatal care (AOR: 1.79; 95% CI: 1.58, 2.04), non-postnatal care (AOR: 1.25; 95%CI: 1.17, 1.35), rural residence(AOR:1.50;95%CI:1.37,1.63), home delivery (AOR: 2.04; 95%CI:1.89, 2.21), having children more than five (AOR: 1.56; 95%CI: 1.13, 2.17), and non-utilization of health insurance (AOR: 1.74; 95%CI: 1.48, 2.05).
The pooled prevalence of incomplete immunization was found to be high in this investigation. Based on the findings of the study we recommended that policymakers and stakeholders prioritize enhancing prenatal and postnatal care, contraception, and reducing home birth rates to minimize the rate of incomplete immunization.
1974 年,世界卫生组织(WHO)设立了扩大免疫规划,以控制可通过疫苗预防的疾病,每年挽救数百万人的生命。然而,非洲所推荐的基本疫苗覆盖率仅为 75%,未达到 2015 年 90%的目标。为制定有效政策和实施计划以降低未完全接种疫苗的比例,确定造成 12-23 月龄儿童未完全免疫的因素非常重要。
本研究在 16 个撒哈拉以南非洲国家开展,数据来源于最新的 DHS 数据。这是一项基于社区的横断面调查,采用两阶段分层概率抽样设计。使用疫苗接种卡和母亲回忆来评估疫苗接种覆盖率。多水平多变量逻辑回归用于确定 12-23 月龄儿童未完全免疫的程度,以及与部分免疫相关的个体和社区水平因素。p 值小于 0.05 的变量被认为是未完全免疫的统计学显著预测因子。
共使用了 35193 个加权样本来确定部分免疫的总体流行率。未完全免疫的总体流行率为 36.06%。在最终模型中,具有统计学显著意义的因素包括:母亲未受教育(AOR:1.75;95%CI:1.48,2.05)、母亲失业(AOR:1.16;95%CI:1.09,1.23)、无计划生育使用史(AOR:1.71;95%CI:1.61,1.84)、无产前护理(AOR:1.79;95%CI:1.58,2.04)、无产后护理(AOR:1.25;95%CI:1.17,1.35)、居住在农村地区(AOR:1.50;95%CI:1.37,1.63)、家庭分娩(AOR:2.04;95%CI:1.89,2.21)、子女多于 5 人(AOR:1.56;95%CI:1.13,2.17)和未使用医疗保险(AOR:1.74;95%CI:1.48,2.05)。
本研究发现未完全免疫的总体流行率较高。根据研究结果,我们建议决策者和利益相关者优先考虑加强产前和产后护理、避孕和降低家庭分娩率,以最大限度地降低未完全免疫的比例。