Lu Tsung-Lung, Huang Chienhsiu
Department of Nursing, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin Town, Chiayi County, Taiwan.
Department of Internal Medicine, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin Town, Chiayi County, Taiwan.
Infect Drug Resist. 2024 May 6;17:1741-1749. doi: 10.2147/IDR.S457781. eCollection 2024.
In recent years, has gained attention for its rare occurrence in patient infections. The literature consists mostly of case reports, necessitating further research to comprehensively understand risk factors, clinical characteristics, and management strategies.
We conducted a retrospective cohort study involving patients diagnosed with infection at a tertiary teaching hospital between January 2014 and December 2022. The data included demographic details, comorbidities, bacterial cultures, antibiotic susceptibility, and treatment outcomes.
There were 26 patients diagnosed with infection who were predominantly older with multiple comorbidities. Approximately 76.9% of infection patients had polymicrobial infections. Twenty-one patients had received antibiotics within three months before they developed the infection, and these antibiotics were primarily third-generation cephalosporins, glycopeptides and fluoroquinolones. Antibiotic susceptibility testing showed resistance to aminoglycosides and susceptibility to imipenem, meropenem, ceftazidime, and piperacillin/tazobactam. Treatment outcome showed a mortality rate of 11.5%, mainly in patients with malignancy and advanced age.
infections predominantly affect older patients with multiple comorbidities. In terms of antibiotic therapy, carbapenems, cephalosporins, and piperacillin/tazobactam with antipseudomonal activity could all be considered.
近年来，[感染类型]因其在患者感染中罕见而受到关注。文献大多为病例报告，需要进一步研究以全面了解危险因素、临床特征和管理策略。
我们进行了一项回顾性队列研究，纳入了2014年1月至2022年12月在一家三级教学医院被诊断为[感染类型]感染的患者。数据包括人口统计学细节、合并症、细菌培养、抗生素敏感性和治疗结果。
有26例被诊断为[感染类型]感染的患者，主要为老年且有多种合并症。约76.9%的[感染类型]感染患者为多重微生物感染。21例患者在发生[感染类型]感染前三个月内接受过抗生素治疗，这些抗生素主要是第三代头孢菌素、糖肽类和氟喹诺酮类。抗生素敏感性测试显示对氨基糖苷类耐药，对亚胺培南、美罗培南、头孢他啶和哌拉西林/他唑巴坦敏感。治疗结果显示死亡率为11.5%，主要发生在恶性肿瘤和高龄患者中。
[感染类型]感染主要影响有多种合并症的老年患者。在抗生素治疗方面，可考虑使用碳青霉烯类、头孢菌素类以及具有抗假单胞菌活性的哌拉西林/他唑巴坦。
