Chen Weifu, Tian Long, Pan Wenjun
Department of Orthopedics, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, Zhejiang, China.
Department of Orthopedics, Langzhong People's Hospital, Langzhong, Sichuan, China.
J Family Med Prim Care. 2024 Mar;13(3):1020-1023. doi: 10.4103/jfmpc.jfmpc_1396_23. Epub 2024 Apr 4.
Anterior cervical discectomy and fusion is the most commonly used surgical approach for treating cervical spine conditions, but it can often lead to postoperative swallowing difficulties. To retrospectively assess the effects of topical triamcinolone acetonide in the anterior cervical surgery on swallowing function.
In this study, a retrospective design was used to select patients aged 18 years and older who were diagnosed with cervical spondylosis and required anterior cervical discectomy and fusion. Among them, the patients in the experimental group used triamcinolone acetonide topically in front of the plate during surgery, and the control group was the patients who did not use triamcinolone acetonide. The sex, age, operation time, operation segment, and preoperative soft tissue area were compared between the two groups.
There were no significant differences in gender, age, operation time, and segment between the two groups. For the preoperative soft tissue area, triamcinolone acetonide was significantly lower than in the control group ( < 0.05).
The retrospective results of this study support that topical triamcinolone acetonide as a treatment in anterior cervical surgery can significantly reduce soft tissue swelling, and no effect was found on the operation time, postoperative blood loss, and segment. These findings provide an important basis for clinical care teams to make treatment decisions and confirm the effectiveness of triamcinolone acetonide in improving swallowing function. However, there was a possibility of information collection and selection bias due to the limitations of retrospective studies. To confirm and further advance the use of this treatment, more rigorous prospective randomized controlled trials are recommended to validate these preliminary results.
颈椎前路椎间盘切除融合术是治疗颈椎疾病最常用的手术方法，但术后常导致吞咽困难。回顾性评估局部应用曲安奈德在颈椎前路手术中对吞咽功能的影响。
本研究采用回顾性设计，选取18岁及以上被诊断为颈椎病且需要行颈椎前路椎间盘切除融合术的患者。其中，实验组患者在手术中于钢板前方局部应用曲安奈德，对照组为未使用曲安奈德的患者。比较两组患者的性别、年龄、手术时间、手术节段及术前软组织面积。
两组患者在性别、年龄、手术时间和节段方面无显著差异。术前软组织面积方面，曲安奈德组显著低于对照组（<0.05）。
本研究的回顾性结果支持局部应用曲安奈德在颈椎前路手术中可显著减轻软组织肿胀，且对手术时间、术后失血量和节段无影响。这些发现为临床护理团队做出治疗决策提供了重要依据，并证实了曲安奈德在改善吞咽功能方面的有效性。然而，由于回顾性研究的局限性，存在信息收集和选择偏倚的可能性。为了证实并进一步推进这种治疗方法的应用，建议进行更严格的前瞻性随机对照试验来验证这些初步结果。
