Arora Aakanksha, Mohta Alpana, Mehta Rajesh Datt, Ghiya Bhikam Chand, Soni Prasoon, Jangir Vishnu Kumar, Yadav Manoj Kumar, Khokhar Rajesh, Mangava Vijay
Department of Dermatology, Venereology and Leprology, Bikaner, Rajasthan, India.
Department of Ophthalmology, Sardar Patel Medical College, Bikaner, Rajasthan, India.
J Cutan Aesthet Surg. 2024 Jan-Mar;17(1):1-6. doi: 10.4103/JCAS.JCAS_157_22.
Xanthelasma palpebrarum (XP) is a benign cosmetic condition. Although the role of CO laser is well described, there are only a few studies on Erbium: YAG in XP. Similarly, trichloroacetic acid (TCA) is commonly used in XP. However, there are only a few studies comparing these modalities in the treatment of XP.
To evaluate the effectiveness and safety of Erbium: YAG laser and 50% TCA in the treatment of XP with the role of dermoscope in the evaluation of lesions.
A total of 20 subjects were randomly allocated into two groups: group A (TCA) and group B (laser). All patients were subcategorized into three grades viz. I (mild), II (moderate), and III (severe) using a self-devised scoring system.
About 25% and 70% of patients achieved complete clearance in groups A and B, respectively ( = 0.017). The rate of recurrence was 40% and 15% in groups A and B. Dyspigmentation and erythema were the most common side effects. Pretreatment dermoscopic evaluation of the lesion showed a network of brown streaks on a background of a yellowish structureless area and was used to assess the area and margins of the lesion where the adipose tissue was found during the procedure and serial assessment of the lesion.
睑黄瘤(XP)是一种良性美容问题。尽管二氧化碳激光的作用已有详尽描述,但关于铒:钇铝石榴石激光治疗睑黄瘤的研究却很少。同样,三氯乙酸(TCA)也常用于睑黄瘤治疗。然而,比较这些治疗方式治疗睑黄瘤的研究也很少。
评估铒:钇铝石榴石激光和50%三氯乙酸治疗睑黄瘤的有效性和安全性,以及皮肤镜在病变评估中的作用。
总共20名受试者被随机分为两组:A组(三氯乙酸组)和B组(激光组)。所有患者使用自行设计的评分系统分为三个等级,即I级(轻度)、II级(中度)和III级(重度)。
A组和B组分别约有25%和70%的患者实现了完全清除(P = 0.017)。A组和B组的复发率分别为40%和15%。色素沉着和红斑是最常见的副作用。术前对病变进行皮肤镜评估显示,在淡黄色无结构区域背景上有棕色条纹网络,用于评估病变的面积和边缘,术中可发现脂肪组织,并对病变进行连续评估。