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沙特关于获得性血友病A诊断与管理的专家共识

Saudi expert consensus on acquired hemophilia A diagnosis and management.

作者信息

Almomen Abdulkareem M, Alzahrani Hazza A, AlSaeed Hussein H, AlAseri Zohair, Mady Ahmed F, Owaidah Tarek

机构信息

Department of Pathology, College of Medicine, King Saud University, Riyadh, KSA.

Adult Hematology/HSCT, Oncology Centre, King Faisal Specialist Hospital and Research Center, Riyadh, KSA.

出版信息

J Taibah Univ Med Sci. 2024 Apr 27;19(3):566-574. doi: 10.1016/j.jtumed.2024.04.006. eCollection 2024 Jun.

Abstract

OBJECTIVES

Acquired hemophilia affects approximately one in 1 million people. Timely diagnosis is key to appropriate disease management and the prevention of life-threatening complications. Patients with this condition may initially be seen by inexperienced physicians and remain underdiagnosed for several years. This consensus statement is aimed at providing guidelines for all practitioners in the Kingdom of Saudi Arabia (KSA) to diagnose and manage acquired hemophilia A.

METHODS

This consensus statement reflects the opinions drafted by a group of hematology specialists, who used an explicit systematic process to identify areas of agreement and disagreement.

RESULTS

This consensus statement provides a guide for all practitioners in the KSA regarding the diagnosis of clinical presentation, relevance, characteristics of bleeding symptoms, and case management; it additionally provides guidance for non-specialists. All management aspects, including diagnosis and treatment modalities, are discussed.

CONCLUSIONS

Patients with acquired hemophilia may initially be seen by physicians who lack appropriate expertise in diagnosing and managing this condition. This consensus statement from the premier experts on the disease in the KSA provides details for diagnosing and managing acquired hemophilia.

摘要

目的

获得性血友病影响约百万分之一的人群。及时诊断是进行恰当疾病管理及预防危及生命并发症的关键。患有这种疾病的患者最初可能由经验不足的医生诊治,并且会在数年时间里一直未得到确诊。本共识声明旨在为沙特阿拉伯王国(KSA)的所有从业者提供诊断和管理获得性血友病A的指南。

方法

本共识声明反映了一组血液学专家起草的意见,他们采用了明确的系统流程来确定一致和不一致的领域。

结果

本共识声明为KSA的所有从业者提供了关于临床表现诊断、相关性、出血症状特征及病例管理的指南;此外还为非专科医生提供了指导。讨论了包括诊断和治疗方式在内的所有管理方面。

结论

获得性血友病患者最初可能由在诊断和管理该疾病方面缺乏适当专业知识的医生诊治。KSA该疾病首要专家的这份共识声明提供了诊断和管理获得性血友病的详细信息。

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