Montatore Manuela, Masino Federica, Muscatella Gianmichele, Gifuni Rossella, Fascia Giacomo, Sciacqua Alessio, Guglielmi Giuseppe
Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71122 Foggia, (FG) Italy.
Radiology Unit, "Dimiccoli" Hospital, Viale Ippocrate 15, 70051, Barletta (BT), Italy.
Radiol Case Rep. 2024 May 3;19(8):2911-2917. doi: 10.1016/j.radcr.2024.03.092. eCollection 2024 Aug.
We report a case of myxofibrosarcoma of the posterior region of the femur, part of the group of soft-tissue sarcomas: a set of rare and heterogeneous tumors with various subtypes and different prognostic. It is characterized by local infiltrative activity and an extremely high rate of local recurrence. A 58-year-old man came to the Radiology Department to examine a voluminous round and expansive formation of the posterior thigh region. The patient stated that the mass had grown suddenly for about 3 months, maybe after a trauma, increasing in volume exponentially and causing him discomfort, embarrassment, and pain. The result of the first diagnostic approach, with the US, was unexpected and suspicious, and the radiologist wanted to do first a CT, and then maybe plan an MRI. The CT revealed an inhomogeneous density formation and in MRI the mass resulted to be compatible, with the radiologic pattern, with the diagnosis of a sarcoma of the soft tissue. The physicians had already alerted the pathological anatomy, as they suspected something malignant. So, some days after the MRI examination, the patient underwent histological sampling, confirming the suspicion: a myxofibrosarcoma (stage III) of the posterior region of the femoral region. The patient started on radio and chemotherapy, which increases survival and in the hope of reducing the size of the mass, and a strict follow-up was posed before doing the surgery.
我们报告一例股骨后部黏液纤维肉瘤病例，其属于软组织肉瘤组：这是一组罕见且异质性的肿瘤，具有多种亚型和不同预后。其特征为局部浸润性生长以及极高的局部复发率。一名58岁男性前往放射科检查大腿后部一个巨大的圆形、膨胀性肿物。患者称该肿物在大约3个月内突然增大，可能是在一次外伤后，体积呈指数级增长，给他带来不适、尴尬和疼痛。初次超声诊断结果出人意料且可疑，放射科医生想先进行CT检查，然后可能再安排MRI检查。CT显示密度不均匀的肿物，MRI检查结果与放射学表现相符，诊断为软组织肉瘤。医生们怀疑是恶性病变，已通知病理解剖科。所以，在MRI检查几天后，患者接受了组织学取样，证实了怀疑：股骨后部黏液纤维肉瘤（III期）。患者开始接受放疗和化疗，这有望提高生存率并缩小肿物大小，在进行手术前进行了严格的随访。
