Tran Minh Ha, Bryarly Michelle, Pruitt Kelden, Ma Ling, Fei Baowei
Center for Imaging and Surgical Innovation, University of Texas at Dallas, Richardson, TX.
Department of Bioengineering, University of Texas at Dallas, Richardson, TX.
Proc SPIE Int Soc Opt Eng. 2024 Jan-Feb;12836. doi: 10.1117/12.3001647. Epub 2024 Mar 12.
In this study, we developed an imaging system that can acquire and produce high-resolution hyperspectral images of the retina. Our system combines the view from a high-resolution RGB camera and a snapshot hyperspectral camera together. The method is fast and can be constructed into a compact imaging device. We tested our system by imaging a calibrated color chart, biological tissues , and a phantom of the human retina. By using image pansharpening methods, we were able to produce a high-resolution hyperspectral image. The images from the hyperspectral camera alone have a spatial resolution of 0.2 mm/pixel, whereas the pansharpened images have a spatial resolution of 0.1 mm/pixel, a 2x increase in spatial resolution. Our method has the potential to capture images of the retina rapidly. Our method preserves both the spatial and spectral fidelity, as shown by comparing the original hyperspectral images with the pansharpened images. The high-resolution hyperspectral imaging device can have a variety of applications in retina examinations.
在本研究中，我们开发了一种成像系统，该系统能够获取并生成视网膜的高分辨率高光谱图像。我们的系统将高分辨率RGB相机和快照高光谱相机的视角结合在一起。该方法速度快，并且可以构建成一个紧凑的成像设备。我们通过对校准色卡、生物组织和人视网膜模型进行成像来测试我们的系统。通过使用图像锐化方法，我们能够生成高分辨率高光谱图像。仅来自高光谱相机的图像的空间分辨率为0.2毫米/像素，而锐化后的图像的空间分辨率为0.1毫米/像素，空间分辨率提高了2倍。我们的方法有潜力快速捕捉视网膜图像。正如通过将原始高光谱图像与锐化后的图像进行比较所示，我们的方法保留了空间和光谱保真度。高分辨率高光谱成像设备在视网膜检查中可以有多种应用。
