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阴道范尼希菌致菌血症和脊椎骨髓炎:男性侵袭性疾病首例报告

Fannyhessea vaginae causing bacteraemia and vertebral osteomyelitis: first report of invasive disease in a male.

作者信息

Jordan Victoria, Akram Ayesha, Pickles Robert, Arnold Alyssa, Naqvi Syeda

机构信息

Department of Microbiology, NSW Health Pathology, John Hunter Hospital, New Lambton Heights, NSW, Australia.

School of Medicine and Public Health, University of Newcastle, Callaghan, NSW, Australia.

出版信息

Access Microbiol. 2024 Apr 24;6(4). doi: 10.1099/acmi.0.000785.v3. eCollection 2024.

DOI:10.1099/acmi.0.000785.v3
PMID:38737801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11083377/
Abstract

(formerly ) is an anaerobic organism commonly associated with female genital flora, with rare cases of invasive disease reported in females. We discuss the case of an 81-year-old male who presented with an acute history of back pain and signs of urinary tract infection in the context of intermittent self-urinary catheterisation. Multiple blood cultures grew with a later finding of lumbar vertebral osteomyelitis as the cause of back pain. Treatment was commenced with ampicillin, later switched to ceftriaxone, with improvement of acute signs of infection. Gram-positive anaerobic organisms including are possibly under-recognised causes of urinary tract particularly in older males. These bacteria may prove challenging to grow in standard protocols for urine culture; anaerobic or extended incubation could be considered particularly in complicated cases of urinary tract infection without an identifiable pathogen.

摘要

(以前)是一种通常与女性生殖道菌群相关的厌氧菌,女性侵袭性疾病的报告病例罕见。我们讨论了一名81岁男性的病例,该患者在间歇性自我导尿的情况下出现急性背痛病史和尿路感染迹象。多次血培养培养出 ,后来发现腰椎骨髓炎是背痛的原因。开始用氨苄西林治疗,后来改用头孢曲松,感染的急性症状有所改善。包括 在内的革兰氏阳性厌氧菌可能是尿路感染未被充分认识的原因,尤其是在老年男性中。这些细菌在标准尿培养方案中可能难以培养;特别是在没有可识别病原体的复杂尿路感染病例中,可以考虑进行厌氧或延长培养。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5e/11083377/8317b2881530/acmi-6-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5e/11083377/8317b2881530/acmi-6-00785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d5e/11083377/8317b2881530/acmi-6-00785-g001.jpg

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本文引用的文献

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A rare bacteremia caused by in a pregnant woman: case report and literature review.孕妇罕见菌血症由 引起:病例报告及文献复习。
Front Cell Infect Microbiol. 2023 Dec 8;13:1278921. doi: 10.3389/fcimb.2023.1278921. eCollection 2023.
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Sexual behavior shapes male genitourinary microbiome composition.性行为塑造男性泌尿生殖系统微生物组组成。
Cell Rep Med. 2023 Mar 21;4(3):100981. doi: 10.1016/j.xcrm.2023.100981.
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Urinary Microbiome of Reproductive-Age Asymptomatic European Women.生殖年龄段无症状欧洲女性的尿微生物组。
Microbiol Spectr. 2022 Dec 21;10(6):e0130822. doi: 10.1128/spectrum.01308-22. Epub 2022 Nov 16.
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First report of a prosthetic joint infection with Fannyhessea (Atopobium) vaginae.首例阴道片球菌(Fannyhessea)引起的人工关节感染报告。
Eur J Clin Microbiol Infect Dis. 2022 Jul;41(7):1023-1027. doi: 10.1007/s10096-022-04461-0. Epub 2022 May 24.
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Vaginal microbiota as an unusual cause of spondylodiscitis.阴道微生物群作为脊椎骨和椎间盘炎的一个不常见病因。
Arch Gynecol Obstet. 2022 Jul;306(1):109-114. doi: 10.1007/s00404-022-06432-4. Epub 2022 Apr 18.
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Urinary tract infections: Should we think about the anaerobic cocci?尿路感染:我们是否应该考虑厌氧球菌?
Anaerobe. 2022 Oct;77:102509. doi: 10.1016/j.anaerobe.2021.102509. Epub 2022 Jan 4.
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