Nahman B J, Van Aman M E, McLemore W E, O'Toole R V
AJR Am J Roentgenol. 1985 Jul;145(1):97-9. doi: 10.2214/ajr.145.1.97.
When the characteristics of 30 biopsy needles were reviewed in a recent study using cadaveric liver tissue, the Rotex needle was judged to yield notable crush artifact, poor histologic preservation, and small sample specimens. In the current review of the Rotex needle in percutaneous lung biopsy in 121 patients, the authors report 98% sensitivity for the presence of malignancy and 94% specificity for the absence of malignancy. Although the Rotex needle has shown poor results in liver substrate studies, it proved more than adequate for obtaining lung tissue and a subsequent diagnosis of pulmonary malignancy. This apparent contradiction is explained by the fact that the diagnosis of lung malignancy can be made from cytopathologic material and does not require histologic specimens in most cases.
在最近一项使用尸体肝脏组织对30种活检针特性进行评估的研究中,Rotex针被判定会产生明显的挤压伪像、组织学保存不佳且样本量小。在当前对121例患者进行经皮肺活检时使用Rotex针的回顾中,作者报告其对恶性肿瘤存在的敏感性为98%,对无恶性肿瘤的特异性为94%。尽管Rotex针在肝脏基质研究中结果不佳,但事实证明它足以获取肺组织并随后诊断肺恶性肿瘤。这种明显的矛盾可以解释为,肺恶性肿瘤的诊断可以根据细胞病理学材料做出,在大多数情况下不需要组织学标本。