先天性、自发性消退性组织细胞增多症：病例报告及文献复习

Congenital, spontaneously regressing histiocytosis: case report and review of the literature.

作者信息

Kapila P K, Grant-Kels J M, Allred C, Forouhar F, Capriglione A M

出版信息

Pediatr Dermatol. 1985 Jul;2(4):312-7. doi: 10.1111/j.1525-1470.1985.tb00472.x.

DOI:10.1111/j.1525-1470.1985.tb00472.x

Abstract

A patient had numerous skin lesions at birth and they regressed over the next few weeks. Results of the peripheral blood smear and bone marrow examinations were normal. The diagnosis of self-healing histiocytosis was substantiated by the clinical course and characteristic histology. This was subsequently confirmed by the electron microscopic finding of Langerhans' granules within the histiocytic cells, which were positive for S100 by immunoperoxidase.

摘要

一名患者出生时即有多处皮肤损害，在接下来的几周内逐渐消退。外周血涂片和骨髓检查结果均正常。自愈性组织细胞增多症的诊断依据临床病程和特征性组织学表现得以证实。随后，通过电子显微镜检查发现组织细胞内存在朗格汉斯颗粒，免疫过氧化物酶染色显示其S100呈阳性，从而进一步证实了该诊断。