Author Affiliations: Houston Methodist Sugar Land Hospital, Outpatient IV Therapy Clinic, Sugar Land, Texas (Clark).
Pamela Clark, RN, BSN, CRNI, has been a registered nurse for 47 years, practicing exclusively in infusion nursing for 40 of those years. She has worked in multiple practice settings, including home health, skilled nursing facilities, free-standing infusion centers, physician office-based infusion centers, and hospital-based infusion centers. Pamela has presented at Infusion Nurses Society conferences on various topics related to infusion nursing and is president of the Greater Houston Area Chapter of the Infusion Nurses Society.
J Infus Nurs. 2024;47(3):163-174. doi: 10.1097/NAN.0000000000000546. Epub 2024 May 10.
There is a direct correlation between being overweight and iron deficiency. Physiological changes occur in obese adipose cells that contribute to the development of iron deficiency (ID) and iron deficiency anemia (IDA). These changes disrupt the normal iron metabolic checks and balances. Furthermore, bariatric surgery can lead to long-term ID and IDA. Oral iron supplementation may not be effective for many of these patients. Intravenous iron infusions can significantly increase the quality of life for individuals experiencing this condition but are also associated with potentially serious complications. Adequate knowledge about intravenous (IV) iron administration can greatly increase the safety of this beneficial therapy. This review article explains the relationship between obesity, ID/IDA, bariatric surgery and the safe administration of IV iron.
超重与缺铁之间存在直接关联。肥胖脂肪细胞的生理变化会导致缺铁（ID）和缺铁性贫血（IDA）的发生。这些变化破坏了正常的铁代谢平衡。此外，减重手术也会导致长期的 ID 和 IDA。对于许多此类患者来说，口服铁补充剂可能无效。静脉内铁输注可以显著提高患有这种疾病的个体的生活质量，但也与潜在的严重并发症相关。充分了解静脉内（IV）铁给药可以大大提高这种有益治疗的安全性。本文综述了肥胖、ID/IDA、减重手术和 IV 铁安全给药之间的关系。
