Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
作者信息
Wang Tianxin, Tang Wenqin, Zhu Xiaolei, Lv Zhenyu, Chen Jiayan, Li Yongze, Sun Xiaoyu, Lv Haoyu, Gu Quanchang, Li Fahui, Wang Jiangyun
机构信息
iHuman Institute, ShanghaiTech University, Shanghai, China.
School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
出版信息
Cell Res. 2024 Aug;34(8):590-593. doi: 10.1038/s41422-024-00968-7. Epub 2024 May 14.
Abstract
摘要
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本文引用的文献
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Structural insights into the human niacin receptor HCA2-G signalling complex.人类烟酸受体 HCA2-G 信号复合物的结构见解。
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Nutritional and metabolic signalling through GPCRs.通过 G 蛋白偶联受体进行营养和代谢信号传递。
FEBS Lett. 2022 Sep;596(18):2364-2381. doi: 10.1002/1873-3468.14441. Epub 2022 Jul 10.
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Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel.琥珀酸为何物？线粒体辅酶 Q 的“哨兵”发挥生理调节作用。
Nat Chem Biol. 2022 May;18(5):461-469. doi: 10.1038/s41589-022-01004-8. Epub 2022 Apr 28.
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Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.细胞外琥珀酸盐通过 SUCNR1/GPR91 介导的 Gq 信号使 M2 巨噬细胞超极化。
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