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拓展桥小脑角手术中脑心相互作用的范围。

Expanding the spectrum on brain-heart interactions in cerebellopontine angle surgeries.

作者信息

Sharma Prachi, Krishnaswami Sharath, Shah Keyur, Surve Rohini M

机构信息

Department of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Department of Neuroanaesthesia and Neurocritical Care, Paras Hospital, Gurugram, Haryana, India.

出版信息

J Neurosci Rural Pract. 2024 Apr-Jun;15(2):384-386. doi: 10.25259/JNRP_21_2024. Epub 2024 Mar 21.

DOI:10.25259/JNRP_21_2024
PMID:38746525
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11090557/
Abstract

Lesions at the cerebellopontine angle (CP angle) are associated with various brain-heart interactions, which can include those from stimulation of the fifth cranial nerve along the scalp incision in a retrosigmoid suboccipital surgical approach. A 27-year-old male patient with recently diagnosed hypertension (on calcium channel blocker) underwent left CP angle lesion decompression. Transient episodes of bradycardia, hypotension, and bradypnea were observed from the skin incision onward, exacerbated during tumor manipulation. Most episodes subsided with cessation of the surgical stimulus while some required intervention. Postoperatively, blood pressure decreased below the pre-operative levels. Thus, trigeminocardiac reflex can occur as early as the skin incision even in a retrosigmoid approach due to stimulation of the mandibular division, when specific risk factors exist. Such episodes may serve as early warning signs for subsequent intraoperative occurrences. Brainstem compression can be a possible etiology of hypertension in young patients. It underscores the importance of considering brain-heart interactions in surgical interventions involving the CP angle.

摘要

小脑脑桥角(CP角)病变与多种脑-心相互作用相关,这可能包括在乙状窦后枕下手术入路中沿头皮切口刺激第五颅神经所引发的相互作用。一名27岁近期诊断为高血压(正在服用钙通道阻滞剂)的男性患者接受了左侧CP角病变减压手术。从皮肤切口开始就观察到心动过缓、低血压和呼吸过缓的短暂发作,在肿瘤操作期间加剧。大多数发作在手术刺激停止后缓解,而有些则需要干预。术后,血压降至术前水平以下。因此,当存在特定风险因素时,即使在乙状窦后入路中,由于下颌支受到刺激,三叉神经心脏反射最早可在皮肤切口时就出现。此类发作可能作为后续术中情况的早期预警信号。脑干受压可能是年轻患者高血压的一个潜在病因。这凸显了在涉及CP角的手术干预中考虑脑-心相互作用的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f8/11090557/70fa9e553378/JNRP-15-384-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f8/11090557/691cabb3b2cb/JNRP-15-384-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f8/11090557/70fa9e553378/JNRP-15-384-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f8/11090557/691cabb3b2cb/JNRP-15-384-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37f8/11090557/70fa9e553378/JNRP-15-384-g002.jpg

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本文引用的文献

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Risk factors associated with trigeminocardiac reflex in patients with trigeminal neuralgia during percutaneous balloon compression: A retrospective cohort study.与经皮球囊压迫术治疗三叉神经痛患者三叉心反射相关的风险因素:一项回顾性队列研究。
Clin Neurol Neurosurg. 2023 Aug;231:107834. doi: 10.1016/j.clineuro.2023.107834. Epub 2023 Jun 14.
2
The Influence of Trigeminocardiac Reflex on Postoperative Cardiac Adverse Events in Patients Undergoing Cerebellopontine Angle Tumor Resections: A Case-Control Study.三叉神经心脏反射对桥小脑角肿瘤切除患者术后心脏不良事件的影响:一项病例对照研究
World Neurosurg. 2023 Apr;172:e291-e298. doi: 10.1016/j.wneu.2023.01.010. Epub 2023 Jan 7.
3
Trigeminal cardiac reflex: new thinking model about the definition based on a literature review.
三叉神经心脏反射:基于文献综述的关于定义的新思维模式
Medicine (Baltimore). 2015 Feb;94(5):e484. doi: 10.1097/MD.0000000000000484.
4
Management of the trigeminocardiac reflex: facts and own experience.三叉神经心脏反射的管理:事实与自身经验
Neurol India. 2009 Jul-Aug;57(4):375-80. doi: 10.4103/0028-3886.55577.
5
Trigemino-cardiac reflex may be refractory to conventional management in adults.三叉神经-心脏反射在成人中可能对传统治疗方法无效。
Acta Neurochir (Wien). 2008 May;150(5):509-10. doi: 10.1007/s00701-008-1516-y.
6
Severe bradycardia and hypotension after connecting negative pressure to the subgaleal drain during craniotomy closure.开颅手术关闭过程中,将负压连接至帽状腱膜下引流管后出现严重心动过缓和低血压。
Br J Anaesth. 2006 May;96(5):608-10. doi: 10.1093/bja/ael063. Epub 2006 Mar 17.
7
Trigeminocardiac reflex during surgery in the cerebellopontine angle.桥小脑角手术中的三叉神经心脏反射
J Neurosurg. 1999 Feb;90(2):215-20. doi: 10.3171/jns.1999.90.2.0215.