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小儿烧伤患者的高代谢研究进展

Update on Hypermetabolism in Pediatric Burn Patients.

作者信息

Layon Sarah A, Williams Austin D, Parham Matthew J, Lee Jong O

机构信息

Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.

Division of Plastic Surgery, Texas Children's Hospital, Houston, Texas.

出版信息

Semin Plast Surg. 2024 Apr 4;38(2):133-144. doi: 10.1055/s-0044-1782649. eCollection 2024 May.

Abstract

Despite advancements in pediatric burn care, the profound hypermetabolic response associated with severe burns remains a multifaceted challenge throughout the continuum of care. Understanding the various physiologic disturbances that constitute hypermetabolism is crucial for a thorough evaluation and for implementing appropriate surgical and nonsurgical interventions. In this article, we describe the pathophysiology and treatment of hypermetabolism in pediatric burn patients with a focus on reducing resting energy requirements, minimizing infection, and optimizing nutrition for patients undergoing frequent surgical intervention.

摘要

尽管小儿烧伤护理取得了进展,但与严重烧伤相关的严重高代谢反应在整个护理过程中仍然是一个多方面的挑战。了解构成高代谢的各种生理紊乱对于全面评估以及实施适当的手术和非手术干预至关重要。在本文中,我们描述了小儿烧伤患者高代谢的病理生理学和治疗方法,重点是降低静息能量需求、减少感染以及为频繁接受手术干预的患者优化营养。

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本文引用的文献

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A Randomized Trial of Enteral Glutamine for Treatment of Burn Injuries.肠内给予谷氨酰胺治疗烧伤随机临床试验。
N Engl J Med. 2022 Sep 15;387(11):1001-1010. doi: 10.1056/NEJMoa2203364. Epub 2022 Sep 9.
5
The Pediatric Burn: Current Trends and Future Directions.小儿烧伤:当前趋势与未来方向。
Anesthesiol Clin. 2020 Sep;38(3):517-530. doi: 10.1016/j.anclin.2020.05.003. Epub 2020 Jul 15.
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Immunological approaches and therapy in burns (Review).烧伤的免疫治疗方法(综述)
Exp Ther Med. 2020 Sep;20(3):2361-2367. doi: 10.3892/etm.2020.8932. Epub 2020 Jun 24.
8
High-Carbohydrate vs High-Fat Nutrition for Burn Patients.高碳水化合物与高脂肪营养用于烧伤患者。
Nutr Clin Pract. 2019 Oct;34(5):688-694. doi: 10.1002/ncp.10396. Epub 2019 Aug 22.
9

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