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本文引用的文献

1
Randomized trial of TAS-102 for refractory metastatic colorectal cancer.TAS-102 治疗难治性转移性结直肠癌的随机试验。
N Engl J Med. 2015 May 14;372(20):1909-19. doi: 10.1056/NEJMoa1414325.
2
A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: the TRUSTS trial.一项比较多柔比星与 trabectedin 在治疗晚期或转移性未治疗软组织肉瘤患者中的疗效的 IIb 期多中心研究:TRUSTS 试验。
Eur J Cancer. 2015 Jul;51(10):1312-20. doi: 10.1016/j.ejca.2015.03.023. Epub 2015 Apr 23.
3
Trabectedin monotherapy after standard chemotherapy versus best supportive care in patients with advanced, translocation-related sarcoma: a randomised, open-label, phase 2 study.多柔比星脂质体与紫杉醇联合方案一线治疗晚期软组织肉瘤的 III 期随机对照临床研究
Lancet Oncol. 2015 Apr;16(4):406-16. doi: 10.1016/S1470-2045(15)70098-7. Epub 2015 Mar 18.
4
Interruption versus continuation of trabectedin in patients with soft-tissue sarcoma (T-DIS): a randomised phase 2 trial.间断或连续使用盐酸多柔比星脂质体(T-DIS)治疗软组织肉瘤患者(T-DIS):一项随机 2 期试验
Lancet Oncol. 2015 Mar;16(3):312-9. doi: 10.1016/S1470-2045(15)70031-8. Epub 2015 Feb 11.
5
Trabectedin as a single-agent treatment of advanced breast cancer after anthracycline and taxane treatment: a multicenter, randomized, phase II study comparing 2 administration regimens.曲贝替定单药治疗蒽环类和紫杉类治疗后的晚期乳腺癌:一项比较两种给药方案的多中心、随机、II期研究。
Clin Breast Cancer. 2014 Dec;14(6):396-404. doi: 10.1016/j.clbc.2014.06.006. Epub 2014 Aug 15.
6
Impact of cytochrome P450 3A4 inducer and inhibitor on the pharmacokinetics of trabectedin in patients with advanced malignancies: open-label, multicenter studies.细胞色素P450 3A4诱导剂和抑制剂对晚期恶性肿瘤患者曲贝替定药代动力学的影响:开放标签、多中心研究
Cancer Chemother Pharmacol. 2014 Oct;74(4):729-37. doi: 10.1007/s00280-014-2554-1. Epub 2014 Aug 7.
7
Phase I and pharmacokinetic study of trabectedin, a DNA minor groove binder, administered as a 24-h continuous infusion in Japanese patients with soft tissue sarcoma.曲贝替定(一种DNA小沟结合剂)在日本软组织肉瘤患者中进行24小时持续输注的I期和药代动力学研究。
Invest New Drugs. 2014 Aug;32(4):691-9. doi: 10.1007/s10637-014-0094-5. Epub 2014 Apr 3.
8
Activity of trabectedin in germline BRCA1/2-mutated metastatic breast cancer: results of an international first-in-class phase II study.Trabectedin 在胚系 BRCA1/2 突变转移性乳腺癌中的活性:一项国际首创的 2 期研究结果。
Ann Oncol. 2014 Jun;25(6):1152-8. doi: 10.1093/annonc/mdu134. Epub 2014 Apr 1.
9
Randomised phase III trial of trabectedin versus doxorubicin-based chemotherapy as first-line therapy in translocation-related sarcomas.随机 III 期试验:曲贝替定对比多柔比星为基础的化疗,作为相关性肉瘤一线治疗。
Eur J Cancer. 2014 Apr;50(6):1137-47. doi: 10.1016/j.ejca.2014.01.012. Epub 2014 Feb 7.
10
Efficacy and safety of trabectedin as an early treatment for advanced or metastatic liposarcoma and leiomyosarcoma.特泊替尼(trabectedin)早期治疗晚期或转移性脂肪肉瘤和 leiomyosarcoma 的疗效和安全性。
Future Oncol. 2014 Jan;10(1):59-68. doi: 10.2217/fon.13.163. Epub 2013 Aug 29.

药物专论:曲贝替定与曲氟尿苷-替匹嘧啶

Drug Monographs: Trabectedin and Trifluridine-Tipiracil.

作者信息

Solimando Dominic A, Waddell J Aubrey

出版信息

Hosp Pharm. 2016 Feb;51(2):120-128. doi: 10.1310/hpj5102-120. Epub 2016 Feb 1.

DOI:10.1310/hpj5102-120
PMID:38746764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11089604/
Abstract

The complexity of cancer chemotherapy requires pharmacists be familiar with the complicated regimens and highly toxic agents used. This column reviews various issues related to preparation, dispensing, and administration of antineoplastic therapy, and the agents, both commercially available and investigational, used to treat malignant diseases.

摘要

癌症化疗的复杂性要求药剂师熟悉所使用的复杂治疗方案和高毒性药物。本专栏回顾了与抗肿瘤治疗的制备、调配和给药相关的各种问题,以及用于治疗恶性疾病的市售和研究性药物。