DNAforge：一种用于核酸线框纳米结构的设计工具。

DNAforge: a design tool for nucleic acid wireframe nanostructures.

机构信息

Department of Computer Science, Aalto University, Finland.

Department of Mathematics and Computer Science, Philipps University of Marburg, Germany.

出版信息

Nucleic Acids Res. 2024 Jul 5;52(W1):W13-W18. doi: 10.1093/nar/gkae367.

DOI:10.1093/nar/gkae367

PMID:38747339

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11223811/

Abstract

DNAforge is an online tool that provides a unified, user-friendly interface to several recent design methods for DNA and RNA wireframe nanostructures, with the possibility of integrating additional methods into the same framework. Currently, DNAforge supports three design methods for DNA nanostructures and two for RNA nanostructures. The tool enables the design, visualisation and sequence generation for highly complex wireframe nanostructures with a simple fully automated process. DNAforge is freely accessible at https://dnaforge.org/.

摘要

DNAforge 是一个在线工具，它为几种最近的 DNA 和 RNA 线框纳米结构设计方法提供了一个统一的、用户友好的界面，并且有可能将其他方法集成到同一个框架中。目前，DNAforge 支持三种 DNA 纳米结构设计方法和两种 RNA 纳米结构设计方法。该工具通过一个简单的全自动流程，实现了高度复杂的线框纳米结构的设计、可视化和序列生成。DNAforge 可在 https://dnaforge.org/ 免费访问。