Department of Periodontology, Universitat Internacional de Catalunya, Barcelona, Spain.
Department of Oral and Maxillofacial Surgery, Universitat Internacional de Catalunya, Barcelona, Spain.
Clin Oral Implants Res. 2024 Jul;35(7):757-770. doi: 10.1111/clr.14282. Epub 2024 May 15.
The objective of this study is to investigate the association of peri-implantitis (PI) and sinus membrane thickening and to assess the resolution of membrane thickening following intervention (implant removal or peri-implantitis treatment) aimed at arresting PI.
Forty-five patients with 61 implants in the posterior maxillary region were retrospectively included in the study. Twenty-four patients were diagnosed with peri-implantitis (PI) and 21 had peri-implant health (PH). Cone-beam computed tomography (CBCT) scans were evaluated to assess maxillary sinus characteristics, including membrane thickening, sinus occupancy and ostium patency. The CBCT scans taken 6 months after intervention aimed at arresting disease (implant removal or treatment of PI) in the PI group were also appraised and compared to baseline scans.
At baseline, all parameters evaluating membrane thickness disorders yielded significant differences between groups (p < .001). Patients with posterior maxillary implants diagnosed with PI were 7× more likely to present membrane thickening compatible with pathology when compared to patients with healthy implants (OR = 7.14; p = .005). Furthermore, the likelihood was 6x greater in implants diagnosed with PI to exhibit moderate membrane thickening (OR = 6.75, p = .001). The patients receiving interventions aimed at arresting PI experienced significant enhancement in all radiographic parameters related to the sinus cavity at the 6-month follow-up (p < .001), though these variations were similarly independent of whether treatment consisted of PI treatment or implant removal.
Maxillary sinus membrane thickening and the permeability/obstruction of the ostium are frequently associated with the presence of PI in posterior implants. Interventions targeting disease resolution effectively reduce membrane thickness to levels compatible with maxillary sinus health.
本研究旨在探讨种植体周围炎（PI）与窦膜增厚的关系，并评估旨在阻止 PI 的干预（种植体去除或治疗种植体周围炎）后膜增厚的缓解情况。
回顾性纳入 45 名上颌后牙区 61 个种植体的患者。24 名患者被诊断为种植体周围炎（PI），21 名患者有种植体周围健康（PH）。通过锥形束计算机断层扫描（CBCT）评估上颌窦特征，包括膜增厚、窦腔占据和窦口通畅性。还评估了 PI 组中旨在阻止疾病（种植体去除或治疗 PI）的干预后 6 个月的 CBCT 扫描，并与基线扫描进行比较。
基线时，所有评估膜厚度异常的参数在两组之间均有显著差异（p<0.001）。与健康种植体相比，被诊断为 PI 的上颌后牙种植体患者发生与病理学相符的膜增厚的可能性高 7 倍（OR=7.14；p=0.005）。此外，被诊断为 PI 的种植体发生中度膜增厚的可能性高 6 倍（OR=6.75，p=0.001）。接受旨在阻止 PI 的干预的患者在 6 个月随访时所有与窦腔相关的放射学参数均显著改善（p<0.001），但无论治疗是 PI 治疗还是种植体去除，这些变化均同样独立。
上颌窦膜增厚和窦口的通透性/阻塞与后牙种植体中 PI 的存在密切相关。针对疾病缓解的干预措施可有效降低膜厚度，使其达到与上颌窦健康相匹配的水平。
