Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Department of Veterinary Medicine, University of Bari, Valenzano, Bari, Italy.
Res Vet Sci. 2024 Jul;174:105289. doi: 10.1016/j.rvsc.2024.105289. Epub 2024 May 4.
Canine enteric coronavirus (CeCoV) is a globally distributed enteric pathogen that causes significant harm to canines. The objective of this systematic review was to examine the global dissemination of CeCoV and assess the potential for infected canines to be exposed to various CeCoV genotypes and subtypes. With an aggregated prevalence of 18.8%, the study predicted regional variations, indicating that CeCoV is an exceptionally prevalent disease. The increased likelihood that infected canines will be asymptomatic is a significant cause for concern, as undetected cases of CeCoV infection could persist and spread the disease. This underscores the significance of ongoing surveillance of CeCoV in order to avert its transmission. Nevertheless, further investigation is necessary in order to ascertain the moderators that significantly impact the prevalence and distribution of distinct subtypes and genotypes of CeCoV. Hence, it is imperative to undertake randomized clinical trials in order to acquire a more accurate understanding of the variables that influence the prevalence of CeCoV. By conducting ongoing surveillance, regional variations in the prevalence of CeCoV in canines can be accounted for, thereby enhancing our comprehension of the illness and ultimately impeding its transmission.
犬冠状病毒（CeCoV）是一种在全球范围内分布的肠道病原体，对犬类造成了严重危害。本系统评价的目的是研究 CeCoV 的全球传播，并评估感染犬接触各种 CeCoV 基因型和亚型的可能性。研究预测的综合患病率为 18.8%，表明存在区域差异，这表明 CeCoV 是一种非常普遍的疾病。感染犬无症状的可能性增加令人担忧，因为未被发现的 CeCoV 感染病例可能持续存在并传播疾病。这强调了持续监测 CeCoV 以避免其传播的重要性。然而，为了确定显著影响 CeCoV 不同亚型和基因型流行和分布的调节因素，还需要进一步的研究。因此，有必要进行随机临床试验，以更准确地了解影响 CeCoV 流行的变量。通过进行持续监测，可以解释犬中 CeCoV 流行率的区域差异，从而增强我们对疾病的理解，并最终阻止其传播。
