利用接触过微生物的“脏”小鼠来改善人类免疫状态和疾病的临床前模型。
Leveraging dirty mice that have microbial exposure to improve preclinical models of human immune status and disease.
作者信息
Liu Qian, Pickett Thames, Hodge Deborah, Rios Carmen, Arnold Michelle, Dong Gang, Hamilton Sara E, Rehermann Barbara
机构信息
Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, DHHS, Rockville, MD, USA.
Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, DHHS, Rockville, MD, USA.
出版信息
Nat Immunol. 2024 Jun;25(6):947-950. doi: 10.1038/s41590-024-01842-9.
Abstract
The National Institute of Allergy and Infectious Diseases (NIAID) hosted a two-day virtual workshop on leveraging microbial exposure to improve mouse models of human immune status and disease. The workshop’s objective was to evaluate the current state of knowledge in the field and to identify gaps, challenges and future directions.
摘要
美国国立过敏与传染病研究所（NIAID）举办了一场为期两天的虚拟研讨会，主题是利用微生物暴露来改进人类免疫状态和疾病的小鼠模型。该研讨会的目标是评估该领域的当前知识状况，并找出差距、挑战和未来方向。
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