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老年精神病学与阿尔茨海默病中的个性化医疗

Personalized medicine in old age psychiatry and Alzheimer's disease.

作者信息

Siafarikas Nikias

机构信息

Department of Geriatric Psychiatry, Akershus University Hospital, Lørenskog, Norway.

出版信息

Front Psychiatry. 2024 May 1;15:1297798. doi: 10.3389/fpsyt.2024.1297798. eCollection 2024.

Abstract

Elderly patients show us unfolded lives with unique individual characteristics. An increasing life span is associated with increasing physical and mental disease burden. Alzheimer's disease (AD) is an increasing challenge in old age. AD cannot be cured but it can be treated. The complexity of old age and AD offer targets for personalized medicine (PM). Targets for stratification of patients, detection of patients at risk for AD or for future targeted therapy are plentiful and can be found in several omic-levels.

摘要

老年患者向我们展示了具有独特个体特征的丰富人生。寿命的延长与身心疾病负担的增加相关。阿尔茨海默病(AD)在老年人群中构成了日益严峻的挑战。AD无法治愈,但可以治疗。老年和AD的复杂性为个性化医疗(PM)提供了靶点。对患者进行分层、检测AD风险患者或未来靶向治疗的靶点众多,可在多个组学层面找到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b23/11094449/059c801937bc/fpsyt-15-1297798-g001.jpg

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