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毛囊性贝克尔痣:一种罕见临床变异型的病例报告

Follicular Becker's Nevus: A Case Report of an Uncommon Clinical Variant.

作者信息

S Anannya, Wahab Afthab Jameela, Jacob Sheba Mariam, R Vimal Chander

机构信息

Department of Dermatology, Saveetha Medical College, Chennai, IND.

Department of Pathology, Saveetha Medical College, Chennai, IND.

出版信息

Cureus. 2024 Apr 14;16(4):e58264. doi: 10.7759/cureus.58264. eCollection 2024 Apr.

Abstract

Pigmented hairy epidermal nevus, also known as Becker's nevus, has a typical description as a unilateral, hairy in appearance, light to dark brown patch with an irregular but clearly defined border. However, the exact aetiopathogenesis is still poorly comprehended. We report the case of a 19-year-old female who presented with asymptomatic brownish-pigmented macular lesions on the right breast that had slowly increased in size over the past three years. Upon cutaneous inspection, the right breast had 3-5 mm rounded and oval perifollicular macules that ranged from light to dark brown hue without increased hair growth. The macules were discrete and in no particular pattern. Dermoscopy of the lesions showed well-defined perifollicular hypopigmentation surrounded by a pigmented network-like pattern. Histopathology of a punch biopsy taken from one of the follicular lesions demonstrated an increase in basal layer pigmentation with elongation of rete ridges and acanthosis, consistent with Becker's nevus. The patient underwent three sittings of diode laser therapy, once in four weeks, with slight improvement in pigmentation.

摘要

色素性毛表皮痣,也称为贝克尔痣,其典型表现为单侧、外观有毛发、呈浅至深棕色的斑片,边界不规则但清晰。然而,其确切病因仍知之甚少。我们报告一例19岁女性病例,其右乳出现无症状的褐色斑疹病变,在过去三年中大小逐渐增大。经皮肤检查,右乳有3 - 5毫米圆形和椭圆形的毛囊周围斑疹,颜色从浅棕色到深棕色,毛发未增多。斑疹分散,无特定形态。病变的皮肤镜检查显示毛囊周围色素减退边界清晰,周围有色素网状图案。取自其中一个毛囊病变的打孔活检组织病理学显示基底层色素沉着增加, rete嵴延长和棘层肥厚,符合贝克尔痣。该患者接受了三次二极管激光治疗,每四周一次,色素沉着略有改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/653d/11094524/e41396b04c11/cureus-0016-00000058264-i01.jpg

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