Tang Runmin, Tan Lixian, Du Xiaokang, Rong Limin, Zhang Liangming
Department of Spine Surgery, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou Guangdong, 510630, P. R. China.
Department of Orthopaedics, Wenshang County People's Hospital, Wenshang Shandong, 272500, P. R. China.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2024 May 15;38(5):550-555. doi: 10.7507/1002-1892.202402028.
To explore the predictive value of the nerve root sedimentation sign in the diagnosis of lumbar spinal stenosis (LSS).
Between January 2019 and July 2021, 201 patients with non-specific low back pain (NS-LBP) who met the selection criteria were retrospectively analyzed. There were 67 males and 134 females, with an age of 50-80 years (mean, 60.7 years). Four intervertebral spaces (L , L , L , L ) of each case were studied, with a total of 804. The nerve root sedimentation sign was positive in 126 intervertebral spaces, and central canal stenosis was found in 203 intervertebral spaces. Progression to symptomatic LSS was determined by follow-up for lower extremity symptoms similar to LSS, combined with central spinal stenosis. Univariate analysis was performed for gender, age, visual analogue scale (VAS) score for low back pain at initial diagnosis, treatment, dural sac cross-sectional area at each intervertebral space, number of spinal stenosis segments, lumbar spinal stenosis grade, positive nerve root sedimentation sign, and number of positive segments between patients in the progression group and non-progression group, and logistic regression analysis was further performed to screen the risk factors for progression to symptomatic LSS in patients with NS-LBP.
All patients were followed up 17-48 months, with an average of 32 months. Of 201 patients with NS-LBP, 35 progressed to symptomatic LSS. Among them, 33 cases also had central spinal stenosis, which was defined as NS-LBP progressing to symptomatic LSS (33 cases in progression group, 168 cases in non-progression group). Univariate analysis showed that CSA at each intervertebral space, the number of spinal stenosis segments, lumbar spinal stenosis grade, whether the nerve root sedimentation sign was positive, and the number of nerve root sedimentation sign positive segments were the influencing factors for the progression to symptomatic LSS ( <0.05); and further logistic regression analysis showed that positive nerve root sedimentation sign increased the risk of progression of NS-LBP to symptomatic LSS ( =8.774, 0.001).
The nerve root sedimentation sign may be associated with the progression of NS-LBP to symptomatic LSS, and it has certain predictive value for the diagnosis of LSS.
探讨神经根沉降征在腰椎管狭窄症(LSS)诊断中的预测价值。
回顾性分析2019年1月至2021年7月间符合入选标准的201例非特异性下腰痛(NS-LBP)患者。其中男性67例,女性134例,年龄50 - 80岁(平均60.7岁)。对每例患者的4个椎间隙(L 、L 、L 、L )进行研究,共804个椎间隙。126个椎间隙神经根沉降征阳性,203个椎间隙存在中央椎管狭窄。通过随访是否出现类似LSS的下肢症状并结合中央椎管狭窄情况来确定是否进展为有症状的LSS。对进展组和非进展组患者的性别、年龄、初诊时腰痛视觉模拟评分(VAS)、治疗情况、各椎间隙硬脊膜囊横截面积、椎管狭窄节段数、腰椎管狭窄分级、神经根沉降征是否阳性以及阳性节段数进行单因素分析,并进一步进行logistic回归分析以筛选NS-LBP患者进展为有症状LSS的危险因素。
所有患者随访17 - 48个月,平均32个月。201例NS-LBP患者中,35例进展为有症状的LSS。其中33例同时存在中央椎管狭窄,将其定义为NS-LBP进展为有症状的LSS(进展组33例,非进展组168例)。单因素分析显示,各椎间隙硬脊膜囊横截面积、椎管狭窄节段数、腰椎管狭窄分级、神经根沉降征是否阳性以及神经根沉降征阳性节段数是进展为有症状LSS的影响因素(<0.05);进一步logistic回归分析显示,神经根沉降征阳性增加了NS-LBP进展为有症状LSS的风险(=8.774,0.001)。
神经根沉降征可能与NS-LBP进展为有症状的LSS有关,对LSS的诊断具有一定的预测价值。