Ramanan Sruthi Priyavadhana, Singh Bipneet, Gandhamaneni Sri Harshini, Sange Ibrahim
Research, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Medicine/Surgery, Saveetha Medical College, Chennai, IND.
Cureus. 2024 Apr 15;16(4):e58343. doi: 10.7759/cureus.58343. eCollection 2024 Apr.
Eosinophilic esophagitis (EoE) is a chronic immune-mediated condition characterized by the eosinophil infiltration of the esophagus (>15 per high power field). Recently, there has been an increase in both the incidence and prevalence of the disease. The common modalities of treatment are dietary modification, proton pump inhibitors, and steroids. However, the United States Food and Drug Administration has not approved any drugs for the treatment of EoE. This review has discussed the role of steroids in the treatment of EoE, focusing on the various formulations of the drug, its dosage, drug delivery, and duration of therapy. The study also covers the common outcomes of steroid therapy and its side effects.
嗜酸性粒细胞性食管炎（EoE）是一种慢性免疫介导性疾病，其特征为食管嗜酸性粒细胞浸润（每高倍视野>15个）。近来，该疾病的发病率和患病率均有所上升。常见的治疗方式包括饮食调整、质子泵抑制剂和类固醇。然而，美国食品药品监督管理局尚未批准任何用于治疗EoE的药物。本综述讨论了类固醇在EoE治疗中的作用，重点关注药物的各种剂型、剂量、给药方式及治疗持续时间。该研究还涵盖了类固醇治疗的常见结果及其副作用。
