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1 岁杂种兔发生广泛转移的骨肉瘤。

Osteosarcoma with widespread metastasis in a 1-year-old crossbred rabbit.

机构信息

Animal Referral Centre, Auckland, New Zealand.

School of Veterinary Science, Massey University, Palmerston North, New Zealand.

出版信息

Vet Radiol Ultrasound. 2024 Sep;65(5):518-522. doi: 10.1111/vru.13385. Epub 2024 May 16.

DOI:10.1111/vru.13385
PMID:38757436
Abstract

A 14-month-old female spayed, small crossbred rabbit presented for assessment of a small, hard subcutaneous nodule in the right axilla. Serum biochemistry showed markedly increased serum ALP activity. A whole-body CT revealed an aggressive, monostotic osteolytic, and productive lesion within the left alveolar process of the maxilla, with erosion of the alveolar bone and secondary premolar depression. Innumerable metastatic osseous masses were present throughout the body, including cerebral, pulmonary, hepatic, subcutaneous, and skeletal muscular metastases. Postmortem findings confirmed widespread, metastatic osteosarcoma, with the primary lesion within the left maxilla.

摘要

一只 14 个月大的雌性去势小杂种兔,因右侧腋窝处有一个小而硬的皮下结节就诊。血清生化检查显示血清碱性磷酸酶活性显著升高。全身 CT 显示上颌骨左牙槽突内有一个侵袭性、单骨性溶骨性、多产性病变,牙槽骨侵蚀和第二前磨牙凹陷。全身有无数转移性骨肿块,包括脑、肺、肝、皮下和骨骼肌转移。尸检结果证实广泛转移性骨肉瘤,原发性病变位于左上颌骨。

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