Tharumakunarajah Ramiyya, Lee Alice, Hawcutt Daniel B, Harman Nicola L, Sinha Ian P
Royal Preston Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK.
Health Data Science, University of Liverpool, Institute of Population Health, Block F Waterhouse Building, Liverpool, UK.
Pulm Ther. 2024 Jun;10(2):155-170. doi: 10.1007/s41030-024-00257-z. Epub 2024 May 17.
Worldwide, over 2 billion children under the age of 5 experience stunting, wasting, or are underweight. Malnutrition contributes to 45% of all deaths in this age group (approximately 3.1 million deaths) [1]. Poverty, food insecurity, suboptimal feeding practices, climate change, and conflict are all contributing factors. Malnutrition causes significant respiratory problems, including increased risk of respiratory infections, impaired lung function, and increased risk of subsequent adult respiratory disease, including asthma, COPD, and lung cancer. Childhood malnutrition not only has serious consequences for children's health but it also has numerous consequences on wellbeing and educational attainment. Childhood malnutrition is a complex and multifaceted problem. However, by understanding and addressing the underlying causes, and investing in prevention and treatment programs, it is possible to maximize children's health and wellbeing on a global scale. This narrative review will focus on the impact of childhood malnutrition on lung development, the consequent respiratory disease, and what actions can be taken to reduce the burden of malnutrition on lung health.
在全球范围内,超过20亿5岁以下儿童存在发育迟缓、消瘦或体重不足的情况。营养不良导致该年龄组中45%的死亡(约310万例死亡)[1]。贫困、粮食不安全、喂养方式不当、气候变化和冲突都是促成因素。营养不良会引发严重的呼吸问题,包括呼吸道感染风险增加、肺功能受损以及后续患成人呼吸道疾病(如哮喘、慢性阻塞性肺疾病和肺癌)的风险增加。儿童期营养不良不仅对儿童健康有严重影响,还对其幸福感和学业成绩有诸多影响。儿童期营养不良是一个复杂且多方面的问题。然而,通过了解和解决潜在原因,并投资于预防和治疗项目,有可能在全球范围内最大限度地提高儿童的健康和幸福感。本叙述性综述将聚焦于儿童期营养不良对肺部发育的影响、随之而来的呼吸道疾病,以及可以采取哪些行动来减轻营养不良对肺部健康的负担。