Department of Pulmonary & Critical Care Medicine, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Department of Gynecology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, PR China.
Medicine (Baltimore). 2024 May 17;103(20):e38185. doi: 10.1097/MD.0000000000038185.
This study aims to evaluate chest computed tomography (CT) findings in hospital patients with primary varicella pneumonia (PVP). We retrospectively analyzed CT images of 77 PVP patients using 3D Slicer, an open-source software, to model lesions and lungs. This retrospective cohort study was approved by the Institutional Review Board (Ethical Committee, Renmin Hospital, Hubei University of Medicine, Shiyan, China) and waived the requirement for written informed consent. The left lung was more frequently and severely affected in PVP, with significant differences between the 2 groups in CT involvement percentage of each lung region, except for total lung inflation. Group A showed higher median percentages of lung collapse compared to Group B. The extent of left lung involvement is a critical predictor of emphysema in PVP patients, highlighting the importance of also monitoring the right lung for more severe cases. Lower emphysema levels correspond to more collapsed and infiltrated lung segments, suggesting a more severe clinical presentation.
本研究旨在评估原发性水痘性肺炎（PVP）住院患者的胸部计算机断层扫描（CT）表现。我们使用 3D Slicer（一种开源软件）对 77 例 PVP 患者的 CT 图像进行回顾性分析，以对病变和肺部进行建模。本回顾性队列研究获得了湖北医药学院附属人民医院（十堰市）机构审查委员会（伦理委员会）的批准，并豁免了书面知情同意书的要求。PVP 中左肺更常受累且更严重，两组患者各肺区 CT 受累百分比差异有统计学意义，除总肺充气外。与组 B 相比，组 A 的肺塌陷中位数百分比更高。左肺受累程度是 PVP 患者肺气肿的重要预测指标，这表明对于更严重的病例，还需要监测右肺。较低的肺气肿水平与更多的塌陷和浸润肺段相对应，提示更严重的临床表现。
