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膈肌起搏治疗通气衰竭

Diaphragm pacing in the treatment of ventilatory failure.

作者信息

Kotzé P L, Verster J, De Villiers S J, Scott A D

出版信息

S Afr Med J. 1985 Aug 17;68(4):223-4.

PMID:3875903
Abstract

Thirty years of clinical and technical research have produced a reliable apparatus for diaphragm pacing. This entails electrical stimulation to the phrenic nerve by a remote radio-frequency transmitter. Prerequisites for diaphragm pacing are adequate alveolar gas exchange, an intact phrenic nerve and diaphragm muscle, and a co-operative patient for the prolonged period of rehabilitation. Diaphragm pacing has been used in cases of central alveolar hypoventilation and chronic obstructive airway disease, as well as for lesions of the cervical cord. To avoid fatigue and possible irreversible injury to the muscle, the right and left hemidiaphragms are paced alternately. We demonstrate the effectiveness of diaphragm pacing for long-term artificial respiration in a patient with transection of the cord at C3/4. The decisive benefit of diaphragm pacing for the quadriplegic patient is that it renders him free of dependence on a mechanical ventilator with its associated social and psychological impediments.

摘要

三十年的临床和技术研究已产生了一种用于膈肌起搏的可靠装置。这需要通过远程射频发射器对膈神经进行电刺激。膈肌起搏的前提条件是充分的肺泡气体交换、完整的膈神经和膈肌,以及在长期康复过程中配合的患者。膈肌起搏已用于中枢性肺泡通气不足和慢性阻塞性气道疾病的病例,以及颈髓损伤。为避免肌肉疲劳和可能的不可逆损伤,左右半膈肌交替起搏。我们展示了膈肌起搏对一名C3/4脊髓横断患者长期人工呼吸的有效性。膈肌起搏对四肢瘫痪患者的决定性益处在于,它使患者摆脱了对伴有相关社会和心理障碍的机械呼吸机的依赖。

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