Department of Neurology, Heyuan People's Hospital, Guangdong Provincial People's Hospital Heyuan Hospital, Heyuan, 517000, Guangdong, China.
Eur J Med Res. 2024 May 17;29(1):289. doi: 10.1186/s40001-024-01853-0.
To explore the imaging and transcranial Doppler cerebral blood flow characteristics of cerebrovascular fenestration malformation and its relationship with the occurrence of ischemic cerebrovascular disease.
A retrospective analysis was conducted on the imaging data of 194 patients with cerebrovascular fenestration malformation who visited the Heyuan People's Hospital from July 2021 to July 2023. The location and morphology of the fenestration malformation blood vessels as well as the presence of other cerebrovascular diseases were analyzed. Transcranial Doppler cerebral blood flow detection data of patients with cerebral infarction and those with basilar artery fenestration malformation were also analyzed.
A total of 194 patients with cerebral vascular fenestration malformation were found. Among the artery fenestration malformation, basilar artery fenestration was the most common, accounting for 46.08% (94/194). 61 patients (31.44%) had other vascular malformations, 97 patients (50%) had cerebral infarction, of which 30 were cerebral infarction in the fenestrated artery supply area. 28 patients with cerebral infarction in the fenestrated artery supply area received standardized antiplatelet, lipid-lowering and plaque-stabilizing medication treatment. During the follow-up period, these patients did not experience any symptoms of cerebral infarction or transient ischemic attack again. There were no differences in peak systolic flow velocity and end diastolic flow velocity, pulsatility index and resistance index between the ischemic stroke group and the no ischemic stroke group in patients with basal artery fenestration malformation (P > 0.05).
Cerebrovascular fenestration malformation is most common in the basilar artery. Cerebrovascular fenestration malformation may also be associated with other cerebrovascular malformations. Standardized antiplatelet and statin lipid-lowering and plaque-stabilizing drugs are suitable for patients with cerebral infarction complicated with fenestration malformation. The relationship between cerebral blood flow changes in basilar artery fenestration malformation and the occurrence of ischemic stroke may not be significant.
探讨脑血管窗畸形的影像学及经颅多普勒脑血流特点及其与缺血性脑血管病发生的关系。
回顾性分析 2021 年 7 月至 2023 年 7 月河源市人民医院收治的 194 例脑血管窗畸形患者的影像学资料，分析窗畸形血管的位置、形态及是否合并其他脑血管病。分析脑梗死患者和基底动脉窗畸形患者的经颅多普勒脑血流检测资料。
共发现脑血管窗畸形 194 例，其中动脉窗畸形以基底动脉窗畸形最为常见，占 46.08%（94/194）。61 例（31.44%）合并其他血管畸形，97 例（50%）合并脑梗死，其中 30 例为窗畸形供血区脑梗死。28 例窗畸形供血区脑梗死患者接受了规范化抗血小板、调脂及稳定斑块治疗，随访期间，这些患者均未再次出现脑梗死或短暂性脑缺血发作症状。基底动脉窗畸形患者中，脑梗死组与无脑梗死组的收缩期峰流速、舒张末期流速、搏动指数、阻力指数比较，差异无统计学意义（P>0.05）。
脑血管窗畸形以基底动脉最为常见，脑血管窗畸形可能与其他脑血管畸形并存。对于合并窗畸形的脑梗死患者，规范化应用抗血小板及他汀类调脂、稳定斑块药物较为适宜。基底动脉窗畸形患者脑血流变化与缺血性脑卒中的发生可能无明显相关性。
