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乳腺圆柱瘤:核心活检乳腺癌的罕见鉴别诊断,病例报告及文献复习。

Cylindroma of the Breast: A Rare Differential for Breast Cancer on Core Biopsies, Case Report and Review of Literature.

机构信息

University of North Dakota, Fargo, USA.

Sanford Medical Center, Fargo, ND, USA.

出版信息

J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241246627. doi: 10.1177/23247096241246627.

DOI:10.1177/23247096241246627
PMID:38761035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11102661/
Abstract

Breast cancers of either ductal or lobular pathology make up the vast majority of breast malignancies. Other cancers occur rarely in the breast. Benign pathology can at times mimic breast cancers on imaging and initial needle biopsies. We report a rare breast pathology of cylindroma. Cylindromas are usually benign, rare dermatologic lesions most commonly associated with head or neck locations. They more commonly occur as sporadic and solitary masses. Less commonly is an autosomal-dominant multi-centric form of this disease. Malignant cylindromas are very rare. We present a patient with findings of a cylindroma of the breast after excision. This was initially felt to be concerning for breast cancer on imaging and core biopsy. Treatment of cylindromas of the breast is excision. Sentinel lymph node dissection is not indicated, nor are adjuvant therapies when identified in the breast. This lesion needs to be included in the differential diagnosis for breast cancer. If cylindromas can be accurately diagnosed preoperatively, this would negate the need for consideration of axillary nodal surgery and adjuvant therapies.

摘要

乳腺的导管或小叶病理学癌症构成了绝大多数的乳腺恶性肿瘤。其他癌症在乳腺中很少见。良性病理学有时在影像学和初始针吸活检上可模拟乳腺癌。我们报告了一种罕见的乳腺圆柱瘤病。圆柱瘤通常是良性的,罕见的皮肤病变,最常与头部或颈部位置相关。它们更常以散发性和孤立性肿块的形式发生。较少见的是这种疾病的常染色体显性多中心形式。恶性圆柱瘤非常罕见。我们报告了一名患者的乳腺圆柱瘤的检查结果。在影像学和核心活检上,最初认为这是乳腺癌。乳腺圆柱瘤的治疗方法是切除。不需要进行前哨淋巴结切除术,也不需要在乳腺中发现时进行辅助治疗。这种病变需要在乳腺癌的鉴别诊断中考虑。如果圆柱瘤可以在术前准确诊断,这将消除对腋窝淋巴结手术和辅助治疗的考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/74fc03e5cc98/10.1177_23247096241246627-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/1c083b563ac4/10.1177_23247096241246627-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/31ed29f25c6f/10.1177_23247096241246627-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/74fc03e5cc98/10.1177_23247096241246627-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/1c083b563ac4/10.1177_23247096241246627-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/31ed29f25c6f/10.1177_23247096241246627-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9573/11102661/74fc03e5cc98/10.1177_23247096241246627-fig3.jpg

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1
Cylindroma of the Breast: A Rare Differential for Breast Cancer on Core Biopsies, Case Report and Review of Literature.乳腺圆柱瘤:核心活检乳腺癌的罕见鉴别诊断,病例报告及文献复习。
J Investig Med High Impact Case Rep. 2024 Jan-Dec;12:23247096241246627. doi: 10.1177/23247096241246627.
2
Fine needle aspiration cytology of breast cylindroma in a woman with familial cylindromatosis: a case report.一名患有家族性圆柱瘤病女性的乳腺圆柱瘤细针穿刺细胞学检查:病例报告
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Primary Cylindroma of the Breast with Brisk Mitosis: A Case Report and Review of Literature.乳腺原发性圆柱瘤伴活跃有丝分裂:病例报告及文献复习。
Int J Surg Pathol. 2023 Aug;31(5):702-707. doi: 10.1177/10668969221117255. Epub 2022 Aug 24.
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本文引用的文献

1
Primary Cylindroma of the Breast with Brisk Mitosis: A Case Report and Review of Literature.乳腺原发性圆柱瘤伴活跃有丝分裂:病例报告及文献复习。
Int J Surg Pathol. 2023 Aug;31(5):702-707. doi: 10.1177/10668969221117255. Epub 2022 Aug 24.
2
Eccrine cylindroma of the face and scalp.面部和头皮的小汗腺圆柱瘤
Indian Dermatol Online J. 2016 May-Jun;7(3):203-5. doi: 10.4103/2229-5178.182355.
3
Breast Neoplasms with Dermal Analogue Differentiation (Mammary Cylindroma): Report of 3 Cases and a Proposal for a New Terminology.
乳腺具有皮肤样分化的肿瘤(乳腺圆柱瘤):3 例报告及新术语建议。
Pathobiology. 2015 Sep;82(3-4):172-8. doi: 10.1159/000433600. Epub 2015 Aug 31.
4
Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing.解决难题:基底样腺样囊性癌还是乳腺圆柱瘤?大规模平行测序的作用。
Histopathology. 2016 Jan;68(2):262-71. doi: 10.1111/his.12735. Epub 2015 Jun 29.
5
Cylindroma of the breast: a rare case report.乳腺圆柱瘤:一例罕见病例报告。
Int J Trichology. 2013 Apr;5(2):83-5. doi: 10.4103/0974-7753.122967.
6
Cylindroma of head and neck: review of the literature and report of two rare cases.头颈部圆柱瘤:文献回顾及两例罕见病例报告。
J Craniomaxillofac Surg. 2013 Sep;41(6):516-21. doi: 10.1016/j.jcms.2012.11.016. Epub 2012 Dec 21.
7
Dermal cylindroma of the scalp.头皮皮肤圆柱瘤
Natl J Maxillofac Surg. 2012 Jan;3(1):59-61. doi: 10.4103/0975-5950.102163.
8
Cylindroma (dermal analog tumor) of the breast: a comparison with cylindroma of the skin and adenoid cystic carcinoma of the breast.乳腺圆柱瘤(皮肤类似物肿瘤):与皮肤圆柱瘤及乳腺腺样囊性癌的比较
Am J Clin Pathol. 2005 Jun;123(6):866-73. doi: 10.1309/CRWU-A3K0-MPQH-QC4W.
9
Cylindroma of the breast of skin adnexal type: a study of 4 cases.皮肤附属器型乳腺圆柱瘤:4例研究
Am J Surg Pathol. 2004 Aug;28(8):1070-5. doi: 10.1097/01.pas.0000126774.27698.27.
10
Solitary cylindroma (dermal analog tumor) of the breast: a previously undescribed neoplasm at this site.乳腺孤立性圆柱瘤(皮肤类似物肿瘤):该部位一种此前未被描述的肿瘤。
Am J Surg Pathol. 2001 Jun;25(6):823-6. doi: 10.1097/00000478-200106000-00017.