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超声引导下骼筋膜间隙阻滞在全髋关节置换术后镇痛中的应用:一项随机对照试验。

Ultrasound-guided suprainguinal fascia iliaca compartment block and early postoperative analgesia after total hip arthroplasty: a randomised controlled trial.

机构信息

Department of Anesthesia, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

University of New South Wales, Sydney, NSW, Australia.

出版信息

Br J Anaesth. 2024 Jul;133(1):146-151. doi: 10.1016/j.bja.2024.04.019. Epub 2024 May 18.

Abstract

BACKGROUND

Hip replacement surgery can be painful; postoperative analgesia is crucial for comfort and to facilitate recovery. Regional anaesthesia can reduce pain and postoperative opioid requirements. The role of ultrasound-guided suprainguinal fascia iliaca block for analgesia after elective total hip arthroplasty is not well defined. This randomised trial evaluated its analgesic efficacy.

METHODS

Consenting participants (134) scheduled for elective primary total hip arthroplasty under spinal anaesthesia were randomly allocated to receive ultrasound-guided fascia iliaca block with ropivacaine 0.5% or sham block with saline. The primary outcome was opioid consumption in the first 24 h after surgery. Additional outcomes included pain scores at 4, 8, 12, and 16 h, opioid-related side-effects (nausea, vomiting, pruritis), ability to perform physiotherapy on the first postoperative day, and physiotherapist-assessed quadriceps weakness.

RESULTS

There were no significant differences in 24-h opioid consumption (block vs sham block, mean difference -3.2 mg oral morphine equivalent, 95% confidence interval -15.3 to 8.1 mg oral morphine equivalent, P=0.55) or any other prespecified outcomes.

CONCLUSIONS

In patients undergoing primary total hip arthroplasty, ultrasound-guided suprainguinal fascia iliaca block with ropivacaine did not confer a significant opioid-sparing effect compared with sham block. There were no differences in other secondary outcomes including pain scores, opioid-related side-effects, or ability to perform physiotherapy on the first postoperative day.

CLINICAL TRIAL REGISTRATION

www.

CLINICALTRIALS

gov (NCT03069183).

摘要

背景

髋关节置换术可能会引起疼痛;术后镇痛对于舒适度和促进康复至关重要。区域麻醉可以减轻疼痛和术后阿片类药物的需求。超声引导下骼筋膜间隙阻滞在择期全髋关节置换术后镇痛中的作用尚未明确。本随机试验评估了其镇痛效果。

方法

选择接受椎管内麻醉下择期初次全髋关节置换术的患者(134 例),并随机分配接受罗哌卡因 0.5%超声引导下骼筋膜间隙阻滞或生理盐水假阻滞。主要结局是术后 24 小时内的阿片类药物消耗量。其他结局包括术后 4、8、12 和 16 小时的疼痛评分、阿片类药物相关副作用(恶心、呕吐、瘙痒)、术后第 1 天进行物理治疗的能力以及物理治疗师评估的股四头肌无力。

结果

24 小时内阿片类药物消耗量(阻滞组与假阻滞组,平均差异-3.2 毫克口服吗啡当量,95%置信区间-15.3 至 8.1 毫克口服吗啡当量,P=0.55)或任何其他预设结局均无显著差异。

结论

在接受初次全髋关节置换术的患者中,与假阻滞相比,超声引导下骼筋膜间隙阻滞罗哌卡因并不能显著节省阿片类药物。其他次要结局(包括疼痛评分、阿片类药物相关副作用或术后第 1 天进行物理治疗的能力)也无差异。

临床试验注册

www.。

临床试验

gov(NCT03069183)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a64/11213984/8933d627d61a/gr1.jpg

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