Ear Institute, Faculty of Brain Sciences, University College London, London, UK.
Hear Res. 2024 Jul;448:109035. doi: 10.1016/j.heares.2024.109035. Epub 2024 May 19.
The sensory epithelia of the auditory and vestibular systems of vertebrates have shared developmental and evolutionary histories. However, while the auditory epithelia show great variation across vertebrates, the vestibular sensory epithelia appear seemingly more conserved. An exploration of the current knowledge of the comparative biology of the amniote utricle, a vestibular sensory epithelium that senses linear acceleration, shows interesting instances of variability between birds and mammals. The distribution of sensory hair cell types, the position of the line of hair bundle polarity reversal and the properties of supporting cells show marked differences, likely impacting vestibular function and hair cell regeneration potential.
脊椎动物的听觉和前庭系统的感觉上皮具有共同的发育和进化历史。然而，尽管听觉上皮在脊椎动物中表现出很大的变异性，但前庭感觉上皮似乎更为保守。对羊膜动物椭圆囊（一种感知线性加速度的前庭感觉上皮）的比较生物学的现有知识的探索表明，鸟类和哺乳动物之间存在有趣的可变性实例。感觉毛细胞类型的分布、毛束极性反转线的位置以及支持细胞的特性显示出明显的差异，可能影响前庭功能和毛细胞再生潜力。
