Yu Qidong, Zhang Wenmin, Wang Jingyi, Xie Shiye, Liao Baodi, Chen Hui, Ding Qingqing, Zhang Lan
Key Laboratory for Analytical Science of Food Safety and Biology (Ministry of Education & Fujian Province), College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China.
Department of Chemistry and Biotechnology, Minjiang Teachers College, Fuzhou, Fujian 350108, China.
J Chromatogr A. 2024 Jul 19;1727:465000. doi: 10.1016/j.chroma.2024.465000. Epub 2024 May 15.
Design and preparation of fiber coatings with excellent electrochemical performance and high polarity is significant for efficient extraction of polar targets in electro-enhanced solid-phase microextraction (EE-SPME). In this work, a combination strategy for structure regulation of covalent organic framework (COF) was proposed to fabricate a nitrogen-rich thiocarbamide linked COF coating (Thiocarbamide-TZ-DHTP) via molecular design and post-synthetic thiocarbamide conversion. The prepared COF coating possesses a large number of O, N, and S functional groups, which not only endow the coating with higher polarity but also significantly enhance its electrochemical performance. The COF coating was used for EE-SPME of polar bisphenols (BPs), demonstrating excellent enrichment efficiency and durability. Subsequently, coupled with gas chromatography-tandem mass spectrometry (GC-MS/MS), a sensitive method was developed for determination of trace BPs. The established method possess wide linear ranges (2.0-800.0 ng L), good correlation coefficients (0.9985-0.9994) and low detection limits (0.1-2.0 ng L). Moreover, the established method had been successfully applied to detection of trace BPs in tea beverage with satisfactory recoveries (81.6 % to 118.6 %). This research provides a feasible pathway for preparing COF coating with excellent electrochemical performance and high polarity for EE-SPME.
设计和制备具有优异电化学性能和高极性的纤维涂层对于电增强固相微萃取（EE-SPME）中极性目标物的高效萃取具有重要意义。在这项工作中，提出了一种共价有机框架（COF）结构调控的组合策略，通过分子设计和合成后硫脲转化制备富氮硫脲连接的COF涂层（硫脲-TZ-DHTP）。制备的COF涂层具有大量的O、N和S官能团，这不仅赋予涂层更高的极性，还显著提高了其电化学性能。该COF涂层用于极性双酚（BPs）的EE-SPME，表现出优异的富集效率和耐久性。随后，结合气相色谱-串联质谱（GC-MS/MS），建立了一种测定痕量BPs的灵敏方法。所建立的方法具有宽线性范围（2.0-800.0 ng/L）、良好的相关系数（0.9985-0.9994）和低检测限（0.1-2.0 ng/L）。此外，所建立的方法已成功应用于茶饮料中痕量BPs的检测，回收率令人满意（81.6%至118.6%）。本研究为制备用于EE-SPME的具有优异电化学性能和高极性的COF涂层提供了一条可行的途径。
