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球囊肺动脉成形术治疗慢性血栓栓塞性肺动脉高压。

Balloon Pulmonary Angioplasty for the Treatment of Chronic Thromboembolic Pulmonary Hypertension.

机构信息

Seattle Children's Hospital, Seattle, Washington, US.

Houston Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US.

出版信息

Methodist Debakey Cardiovasc J. 2024 May 16;20(3):57-64. doi: 10.14797/mdcvj.1347. eCollection 2024.

Abstract

Chronic thromboembolic pulmonary hypertension is a rare form of pulmonary hypertension in patients who have evidence of chronic thromboembolic occlusion of the pulmonary vasculature. Historically, surgical pulmonary thromboendarterectomy has been the treatment of choice. However, with up to 40% of patients deemed inoperable, balloon pulmonary angioplasty has emerged as an additional treatment strategy. Balloon pulmonary angioplasty is a complementary strategy alongside surgical pulmonary thromboendarterectomy and offers the opportunity for pulmonary revascularization in patients who have more distal disease, higher comorbidities, or residual obstruction following operative intervention. This review examines the history of balloon pulmonary angioplasty, highlights its effectiveness, discusses important complications and risk reduction strategies, and emphasizes the importance of centers forming a multidisciplinary team of providers to manage the complexity of patients with chronic thromboembolic pulmonary hypertension.

摘要

慢性血栓栓塞性肺动脉高压是一种罕见的肺动脉高压形式,发生于存在肺动脉血管慢性血栓栓塞闭塞证据的患者中。在历史上,手术肺动脉血栓内膜切除术一直是首选治疗方法。然而,多达 40%的患者被认为无法手术,球囊肺动脉成形术已成为一种额外的治疗策略。球囊肺动脉成形术是手术肺动脉血栓内膜切除术的补充策略,为那些存在更远端疾病、更高合并症或手术干预后仍有残留阻塞的患者提供了肺血运重建的机会。本综述探讨了球囊肺动脉成形术的历史,强调了其有效性,讨论了重要的并发症和降低风险策略,并强调了形成多学科提供者团队来管理慢性血栓栓塞性肺动脉高压患者复杂性的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1c6/11100548/e7e7aec182c8/mdcvj-20-3-1347-g1.jpg

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