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虚弱和身体功能不佳是导致驾驶能力丧失的危险因素。

Frailty and poor physical functioning as risk factors for driving cessation.

机构信息

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, United States.

Center for Injury Science and Prevention, Columbia University Irving Medical Center, New York, NY, United States.

出版信息

Front Public Health. 2024 May 3;12:1298539. doi: 10.3389/fpubh.2024.1298539. eCollection 2024.

Abstract

INTRODUCTION

Frailty and low physical performance are modifiable factors and, therefore, targets for interventions aimed at delaying driving cessation (DC). The objective was to determine the impact of frailty and physical performance on DC.

METHODS

Multisite prospective cohort of older drivers. The key inclusion criteria are as follows: active driver age 65-79 years, possessing a valid driver's license, without significant cognitive impairment, and driving a 1996 car or a newer model car. Of the 2,990 enrolled participants, 2,986 (99.9%) had at least one frailty or Short Physical Performance Battery (SPPB) measure and were included in this study. In total, 42% of participants were aged 65-69 years, 86% were non-Hispanic white, 53% were female, 63% were married, and 41% had a high degree of education. The Fried Frailty Phenotype and the Expanded Short Physical Performance Battery (SPPB) from the National Health and Aging Trends Study were utilized. At each annual visit, DC was assessed by the participant notifying the study team or self-reporting after no driving activity for at least 30 days, verified via GPS. Cox proportional hazard models, including time-varying covariates, were used to examine the impact of the SPPB and frailty scores on time to DC. This assessment included examining interactions by sex.

RESULTS

Seventy-three participants (2.4%) stopped driving by the end of year 5. Among women with a fair SPPB score, the adjusted hazard ratio (HR) of DC was 0.26 (95% confidence interval (CI) 0.10-0.65) compared to those with a poor SPPB score. For those with a good SPPB score, the adjusted HR of DC had a -value of <0.001. Among men with a fair SPPB score, the adjusted hazard ratio (HR) of DC was 0.45 (95% CI 0.25-0.81) compared to those with a poor SPPB score. For men with a good SPPB score, the adjusted HR of DC was 0.19 (95% CI 0.10-0.36). Sex was not an effect modifier between frailty and DC. For those who were categorized into pre-frail or frail, the adjusted ratio of HR to DC was 6.1 (95% CI 2.7-13.8) compared to those who were not frail.

CONCLUSION AND RELEVANCE

Frailty and poor physical functioning are major risk factors for driving cessation. Staying physically active may help older adults to extend their driving life expectancy and mobility.

摘要

介绍

虚弱和身体机能下降是可改变的因素,因此是旨在延迟驾驶停止(DC)的干预措施的目标。目的是确定虚弱和身体机能对 DC 的影响。

方法

多地点前瞻性老年驾驶员队列。主要纳入标准如下:65-79 岁的活跃驾驶员,持有有效驾照,无明显认知障碍,驾驶 1996 年或更新的车型。在 2990 名登记参与者中,2986 名(99.9%)至少有一项虚弱或简短身体表现电池(SPPB)测量值,并纳入本研究。在总共 42%的参与者中,42%的参与者年龄在 65-69 岁之间,86%是非西班牙裔白人,53%为女性,63%已婚,41%受过高等教育。使用了国家健康与老龄化趋势研究中的弗莱德虚弱表型和扩展简短身体表现电池(SPPB)。在每年的就诊中,通过参与者通知研究小组或在至少 30 天没有驾驶活动后自我报告来评估 DC,通过 GPS 验证。使用包含时变协变量的 Cox 比例风险模型来检查 SPPB 和虚弱评分对 DC 时间的影响。这一评估包括通过性别检查交互作用。

结果

73 名参与者(2.4%)在第 5 年末停止驾驶。在 SPPB 评分一般的女性中,与 SPPB 评分较差的女性相比,DC 的调整后的危险比(HR)为 0.26(95%置信区间(CI)0.10-0.65)。对于 SPPB 评分良好的女性,DC 的调整后 HR 值为<0.001。在 SPPB 评分一般的男性中,与 SPPB 评分较差的男性相比,DC 的调整后的危险比(HR)为 0.45(95%置信区间(CI)0.25-0.81)。对于 SPPB 评分良好的男性,DC 的调整后 HR 为 0.19(95%置信区间(CI)0.10-0.36)。性别不是虚弱和 DC 之间的效应修饰剂。对于被归类为虚弱或虚弱的人,与非虚弱的人相比,调整后的 HR 比值为 6.1(95%置信区间(CI)2.7-13.8)。

结论和相关性

虚弱和身体机能下降是驾驶停止的主要危险因素。保持身体活跃可能有助于老年人延长驾驶预期寿命和行动能力。

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